BRD-A18328003_GDC-0980_MDAMB231_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A18328003_GDC-0980_MDAMB231_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
ADCK3 aarF domain containing kinase 3
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEMIP cell migration inducing protein, hyaluronan binding
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DMBT1 deleted in malignant brain tumors 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FAM129A family with sequence similarity 129, member A
GATA6 GATA binding protein 6
GLUL glutamate-ammonia ligase
HMGB2 high mobility group box 2
IGHM immunoglobulin heavy constant mu
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
JADE2 jade family PHD finger 2
LYZ lysozyme
MFAP4 microfibrillar-associated protein 4
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
NMU neuromedin U
NUPR1 nuclear protein, transcriptional regulator, 1
PITX1 paired-like homeodomain 1
PLS3 plastin 3
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RALGDS ral guanine nucleotide dissociation stimulator
S100A7 S100 calcium binding protein A7
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFRP1 secreted frizzled-related protein 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLN sarcolipin
STC1 stanniocalcin 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR3 transforming growth factor, beta receptor III
TGIF1 TGFB-induced factor homeobox 1
TOB1 transducer of ERBB2, 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRBC1 T cell receptor beta constant 1
TSC22D1 TSC22 domain family, member 1
TXNIP thioredoxin interacting protein
VWF von Willebrand factor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ANOS1 anosmin 1
BIRC2 baculoviral IAP repeat containing 2
CDC25A cell division cycle 25A
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GJA1 gap junction protein, alpha 1, 43kDa
GRIA2 glutamate receptor, ionotropic, AMPA 2
ITGB1BP1 integrin beta 1 binding protein 1
JMJD6 jumonji domain containing 6
KDM5D lysine (K)-specific demethylase 5D
KRT23 keratin 23, type I
LUM lumican
MBP myelin basic protein
MNDA myeloid cell nuclear differentiation antigen
NPY1R neuropeptide Y receptor Y1
NRG1 neuregulin 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLP1 proteolipid protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SNAP25 synaptosomal-associated protein, 25kDa
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)