BRD-A18328003_GDC-0980_MDAMB231_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-A18328003_GDC-0980_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANGPT1 angiopoietin 1
ANXA1 annexin A1
ANXA11 annexin A11
ANXA4 annexin A4
BACE2 beta-site APP-cleaving enzyme 2
BCL6 B-cell CLL/lymphoma 6
BHLHE41 basic helix-loop-helix family, member e41
CD59 CD59 molecule, complement regulatory protein
CD93 CD93 molecule
CLU clusterin
DHRS3 dehydrogenase/reductase (SDR family) member 3
ETV1 ets variant 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRN granulin
GSN gelsolin
HBP1 HMG-box transcription factor 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIAA1033 KIAA1033
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAMP2 lysosomal-associated membrane protein 2
LGALS3 lectin, galactoside-binding, soluble, 3
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
NES nestin
NIPSNAP1 nipsnap homolog 1 (C. elegans)
OLFM4 olfactomedin 4
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLIN2 perilipin 2
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RB1CC1 RB1-inducible coiled-coil 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
TM4SF1 transmembrane 4 L six family member 1
TPP1 tripeptidyl peptidase I
TPST2 tyrosylprotein sulfotransferase 2
TSPAN8 tetraspanin 8
VNN1 vanin 1
VWF von Willebrand factor

decreased expression

Symbol Name
ADM adrenomedullin
BARD1 BRCA1 associated RING domain 1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CENPU centromere protein U
CTPS1 CTP synthase 1
CXCL13 chemokine (C-X-C motif) ligand 13
DHFR dihydrofolate reductase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FEN1 flap structure-specific endonuclease 1
FGFBP1 fibroblast growth factor binding protein 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GSTM3 glutathione S-transferase mu 3 (brain)
HMGB2 high mobility group box 2
IGFBP5 insulin-like growth factor binding protein 5
LMNB1 lamin B1
MCM3 minichromosome maintenance complex component 3
NT5DC2 5'-nucleotidase domain containing 2
PCNA proliferating cell nuclear antigen
PHTF2 putative homeodomain transcription factor 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
RRM2 ribonucleotide reductase M2
S100A2 S100 calcium binding protein A2
SESN1 sestrin 1
SMC1A structural maintenance of chromosomes 1A
SPRR1A small proline-rich protein 1A
SRM spermidine synthase
TUBG1 tubulin, gamma 1
ZWINT ZW10 interacting kinetochore protein