BRD-A18328003_GDC-0980_MDAMB231_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A18328003_GDC-0980_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOD apolipoprotein D
BCL6 B-cell CLL/lymphoma 6
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DUSP6 dual specificity phosphatase 6
FABP4 fatty acid binding protein 4, adipocyte
FAM189A2 family with sequence similarity 189, member A2
GLUL glutamate-ammonia ligase
HBP1 HMG-box transcription factor 1
HLA-E major histocompatibility complex, class I, E
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IRS2 insulin receptor substrate 2
KLHL24 kelch-like family member 24
KRT18 keratin 18, type I
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDGFRL platelet-derived growth factor receptor-like
PIP prolactin-induced protein
PPAP2C phosphatidic acid phosphatase type 2C
RNASET2 ribonuclease T2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TPP1 tripeptidyl peptidase I
TRAPPC6A trafficking protein particle complex 6A

decreased expression

Symbol Name
CDC20 cell division cycle 20
GINS1 GINS complex subunit 1 (Psf1 homolog)
MMP12 matrix metallopeptidase 12
NT5DC2 5'-nucleotidase domain containing 2
PCCB propionyl CoA carboxylase, beta polypeptide
PGAM1 phosphoglycerate mutase 1 (brain)
RRM2 ribonucleotide reductase M2
TUBG1 tubulin, gamma 1