BRD-A18328003_GDC-0980_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-A18328003_GDC-0980_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ASPN asporin
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD163 CD163 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CRISP3 cysteine-rich secretory protein 3
CYR61 cysteine-rich, angiogenic inducer, 61
DFNA5 deafness, autosomal dominant 5
DSP desmoplakin
ECM1 extracellular matrix protein 1
GLUL glutamate-ammonia ligase
GSN gelsolin
HIST1H1C histone cluster 1, H1c
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGL immunoglobulin lambda locus
MAOA monoamine oxidase A
MT1X metallothionein 1X
NPDC1 neural proliferation, differentiation and control, 1
NT5E 5'-nucleotidase, ecto (CD73)
RFTN1 raftlin, lipid raft linker 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEPP1 selenoprotein P, plasma, 1
SFRP4 secreted frizzled-related protein 4
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TBX3 T-box 3
TIMP3 TIMP metallopeptidase inhibitor 3
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
CDC25A cell division cycle 25A
CYCS cytochrome c, somatic
DEFB1 defensin, beta 1
EIF5A eukaryotic translation initiation factor 5A
GLIPR1 GLI pathogenesis-related 1
GSTP1 glutathione S-transferase pi 1
LAGE3 L antigen family, member 3
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
TLR4 toll-like receptor 4