BRD-A18328003_GDC-0980_MCF10A_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

131 genes differentially expressed following the BRD-A18328003_GDC-0980_MCF10A_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
APOD apolipoprotein D
ASS1 argininosuccinate synthase 1
BASP1 brain abundant, membrane attached signal protein 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
C6ORF48 chromosome 6 open reading frame 48
CAV1 caveolin 1, caveolae protein, 22kDa
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC109B coiled-coil domain containing 109B
CCNG2 cyclin G2
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELF2 CUGBP, Elav-like family member 2
CFD complement factor D (adipsin)
CFH complement factor H
CHRDL1 chordin-like 1
CNPY3 canopy FGF signaling regulator 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSRP2 cysteine and glycine-rich protein 2
CTBP2 C-terminal binding protein 2
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DST dystonin
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
EMP2 epithelial membrane protein 2
EPS8 epidermal growth factor receptor pathway substrate 8
FAM13A family with sequence similarity 13, member A
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
GLUL glutamate-ammonia ligase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX3 glutathione peroxidase 3
HBP1 HMG-box transcription factor 1
IFITM1 interferon induced transmembrane protein 1
IGF1R insulin-like growth factor 1 receptor
IGKV4-1 immunoglobulin kappa variable 4-1
KIAA0485 uncharacterized LOC57235
KLHL24 kelch-like family member 24
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LRP4 low density lipoprotein receptor-related protein 4
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTUS1 microtubule associated tumor suppressor 1
NMU neuromedin U
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDZK1 PDZ domain containing 1
PEX11A peroxisomal biogenesis factor 11 alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC8 placenta-specific 8
PLCB4 phospholipase C, beta 4
PROCR protein C receptor, endothelial
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC16A4 solute carrier family 16, member 4
SLC38A1 solute carrier family 38, member 1
SOX4 SRY (sex determining region Y)-box 4
STOM stomatin
SYNE2 spectrin repeat containing, nuclear envelope 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP4 TIMP metallopeptidase inhibitor 4
TMSB15A thymosin beta 15a
TSC22D3 TSC22 domain family, member 3
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WISP2 WNT1 inducible signaling pathway protein 2
ZIC1 Zic family member 1

decreased expression

Symbol Name
AK1 adenylate kinase 1
APOA2 apolipoprotein A-II
APOE apolipoprotein E
BHLHE40 basic helix-loop-helix family, member e40
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
CDC25A cell division cycle 25A
CHMP6 charged multivesicular body protein 6
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CPB1 carboxypeptidase B1 (tissue)
CTSZ cathepsin Z
DUSP2 dual specificity phosphatase 2
EGR2 early growth response 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FKBP1B FK506 binding protein 1B, 12.6 kDa
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GNAS GNAS complex locus
H1F0 H1 histone family, member 0
HBEGF heparin-binding EGF-like growth factor
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IL1B interleukin 1, beta
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KRT19 keratin 19, type I
KRT23 keratin 23, type I
MEIS2 Meis homeobox 2
MXRA7 matrix-remodelling associated 7
NDFIP1 Nedd4 family interacting protein 1
PDGFC platelet derived growth factor C
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSPH phosphoserine phosphatase
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
SATB1 SATB homeobox 1
SDC4 syndecan 4
SFRP4 secreted frizzled-related protein 4
SIRT3 sirtuin 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPRR3 small proline-rich protein 3
TPST2 tyrosylprotein sulfotransferase 2
TYMP thymidine phosphorylase
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing