BRD-A18328003_GDC-0980_MCF10A_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

244 genes differentially expressed following the BRD-A18328003_GDC-0980_MCF10A_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AES amino-terminal enhancer of split
APOD apolipoprotein D
AREG amphiregulin
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
ASMTL acetylserotonin O-methyltransferase-like
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP9A ATPase, class II, type 9A
BASP1 brain abundant, membrane attached signal protein 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
C1RL complement component 1, r subcomponent-like
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CDH13 cadherin 13
CECR1 cat eye syndrome chromosome region, candidate 1
CFB complement factor B
CFD complement factor D (adipsin)
CFLAR CASP8 and FADD-like apoptosis regulator
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CST1 cystatin SN
CTSD cathepsin D
CTSS cathepsin S
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIAPH2 diaphanous-related formin 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP22 dual specificity phosphatase 22
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
F2R coagulation factor II (thrombin) receptor
FBLN1 fibulin 1
FBN1 fibrillin 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGD6 FYVE, RhoGEF and PH domain containing 6
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOXO3 forkhead box O3
GAA glucosidase, alpha; acid
GAS6 growth arrest-specific 6
GBP2 guanylate binding protein 2, interferon-inducible
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPX4 glutathione peroxidase 4
GRN granulin
GSN gelsolin
GSTZ1 glutathione S-transferase zeta 1
GUSBP3 glucuronidase, beta pseudogene 3
HBP1 HMG-box transcription factor 1
HEBP2 heme binding protein 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IDS iduronate 2-sulfatase
IFITM1 interferon induced transmembrane protein 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
KDM3A lysine (K)-specific demethylase 3A
KRT19 keratin 19, type I
LAMC2 laminin, gamma 2
LOC100272216 uncharacterized LOC100272216
LRP10 low density lipoprotein receptor-related protein 10
LTBP2 latent transforming growth factor beta binding protein 2
LUM lumican
LXN latexin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP1B microtubule-associated protein 1B
MKNK2 MAP kinase interacting serine/threonine kinase 2
MME membrane metallo-endopeptidase
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
N4BP2L1 NEDD4 binding protein 2-like 1
NMRK1 nicotinamide riboside kinase 1
NPDC1 neural proliferation, differentiation and control, 1
NPEPL1 aminopeptidase-like 1
NT5E 5'-nucleotidase, ecto (CD73)
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OPTN optineurin
ORAI3 ORAI calcium release-activated calcium modulator 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCBP2 poly(rC) binding protein 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PGLS 6-phosphogluconolactonase
PNRC1 proline-rich nuclear receptor coactivator 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRAF2 PRA1 domain family, member 2
PROM1 prominin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTK2B protein tyrosine kinase 2 beta
PYCARD PYD and CARD domain containing
R3HDM4 R3H domain containing 4
RAB13 RAB13, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBKS ribokinase
RNASE4 ribonuclease, RNase A family, 4
RPS27L ribosomal protein S27-like
SEC14L1 SEC14-like 1 (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC22A18 solute carrier family 22, member 18
SLC38A2 solute carrier family 38, member 2
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAP2 signal transducing adaptor family member 2
STC1 stanniocalcin 1
SULF1 sulfatase 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TCF4 transcription factor 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TP53TG1 TP53 target 1 (non-protein coding)
TPP1 tripeptidyl peptidase I
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
TUBA1A tubulin, alpha 1a
VAT1 vesicle amine transport 1
VCAN versican
VNN1 vanin 1
WDR45 WD repeat domain 45
WDTC1 WD and tetratricopeptide repeats 1
YPEL5 yippee-like 5 (Drosophila)
ZBTB16 zinc finger and BTB domain containing 16
ZNF277 zinc finger protein 277

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
AMD1 adenosylmethionine decarboxylase 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
CEP55 centrosomal protein 55kDa
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIAPIN1 cytokine induced apoptosis inhibitor 1
CKS2 CDC28 protein kinase regulatory subunit 2
CXCL14 chemokine (C-X-C motif) ligand 14
DBF4 DBF4 zinc finger
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEPDC1 DEP domain containing 1
DIO2 deiodinase, iodothyronine, type II
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLK1 delta-like 1 homolog (Drosophila)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EXOSC9 exosome component 9
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FEN1 flap structure-specific endonuclease 1
FGFR3 fibroblast growth factor receptor 3
FOSL1 FOS-like antigen 1
GAL galanin/GMAP prepropeptide
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GTSE1 G-2 and S-phase expressed 1
HAT1 histone acetyltransferase 1
HIST1H4C histone cluster 1, H4c
HSPA14 heat shock 70kDa protein 14
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
LBR lamin B receptor
LEF1 lymphoid enhancer-binding factor 1
LMNB1 lamin B1
LRRC59 leucine rich repeat containing 59
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAK16 MAK16 homolog (S. cerevisiae)
MCM10 minichromosome maintenance complex component 10
MELK maternal embryonic leucine zipper kinase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAV3 neuron navigator 3
NCAPG non-SMC condensin I complex, subunit G
NCAPG2 non-SMC condensin II complex, subunit G2
NCAPH non-SMC condensin I complex, subunit H
NDC1 NDC1 transmembrane nucleoporin
NEFL neurofilament, light polypeptide
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEK2 NIMA-related kinase 2
NOP56 NOP56 ribonucleoprotein
NPTX2 neuronal pentraxin II
NPY neuropeptide Y
PARP2 poly (ADP-ribose) polymerase 2
PBK PDZ binding kinase
PCDH9 protocadherin 9
PHGDH phosphoglycerate dehydrogenase
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPIF peptidylprolyl isomerase F
PRC1 protein regulator of cytokinesis 1
PSAT1 phosphoserine aminotransferase 1
PSRC1 proline/serine-rich coiled-coil 1
RAD23B RAD23 homolog B (S. cerevisiae)
RAD51C RAD51 paralog C
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RRM2 ribonucleotide reductase M2
SCG2 secretogranin II
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHCBP1 SHC SH2-domain binding protein 1
SMC2 structural maintenance of chromosomes 2
SNAP25 synaptosomal-associated protein, 25kDa
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SPC25 SPC25, NDC80 kinetochore complex component
SPDL1 spindle apparatus coiled-coil protein 1
SRSF3 serine/arginine-rich splicing factor 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACC3 transforming, acidic coiled-coil containing protein 3
TFAM transcription factor A, mitochondrial
TIPIN TIMELESS interacting protein
TMPO thymopoietin
TMX2 thioredoxin-related transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TRA2B transformer 2 beta homolog (Drosophila)
UBE2S ubiquitin-conjugating enzyme E2S
VRK1 vaccinia related kinase 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZWINT ZW10 interacting kinetochore protein