BRD-A18328003_GDC-0980_HT29_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

145 genes differentially expressed following the BRD-A18328003_GDC-0980_HT29_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
ADIRF adipogenesis regulatory factor
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA4 annexin A4
APOD apolipoprotein D
ARMCX1 armadillo repeat containing, X-linked 1
ATP9A ATPase, class II, type 9A
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
C14ORF132 chromosome 14 open reading frame 132
C6ORF48 chromosome 6 open reading frame 48
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNG2 cyclin G2
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK19 cyclin-dependent kinase 19
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCA1 chloride channel accessory 1
CLDN3 claudin 3
CTGF connective tissue growth factor
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
EDN1 endothelin 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERBB3 erb-b2 receptor tyrosine kinase 3
FAIM Fas apoptotic inhibitory molecule
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FNBP1L formin binding protein 1-like
FOXO4 forkhead box O4
GLTSCR2 glioma tumor suppressor candidate region gene 2
GSN gelsolin
HBP1 HMG-box transcription factor 1
HIST3H2A histone cluster 3, H2a
HLA-B major histocompatibility complex, class I, B
HLA-E major histocompatibility complex, class I, E
IDS iduronate 2-sulfatase
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IGFBP7 insulin-like growth factor binding protein 7
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
KRT20 keratin 20, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
MT1E metallothionein 1E
MT1F metallothionein 1F
MTMR11 myotubularin related protein 11
MVP major vault protein
MYO1D myosin ID
N4BP2L2 NEDD4 binding protein 2-like 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCCA propionyl CoA carboxylase, alpha polypeptide
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLSCR4 phospholipid scramblase 4
PRUNE2 prune homolog 2 (Drosophila)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGER4 prostaglandin E receptor 4 (subtype EP4)
QARS glutaminyl-tRNA synthetase
RAP1GAP RAP1 GTPase activating protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RPS4Y1 ribosomal protein S4, Y-linked 1
RSRP1 arginine/serine-rich protein 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3YL1 SH3 and SYLF domain containing 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SYBU syntabulin (syntaxin-interacting)
TFPI2 tissue factor pathway inhibitor 2
TMEM30B transmembrane protein 30B
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM2 tripartite motif containing 2
TRIM22 tripartite motif containing 22
TSPAN31 tetraspanin 31
VDAC1 voltage-dependent anion channel 1
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WDR45 WD repeat domain 45
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ATG3 autophagy related 3
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CIT citron rho-interacting serine/threonine kinase
CKS2 CDC28 protein kinase regulatory subunit 2
COL4A5 collagen, type IV, alpha 5
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMP3 epithelial membrane protein 3
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
GINS2 GINS complex subunit 2 (Psf2 homolog)
HN1 hematological and neurological expressed 1
HSPA14 heat shock 70kDa protein 14
HSPA4L heat shock 70kDa protein 4-like
IL1RN interleukin 1 receptor antagonist
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT13 keratin 13, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LRRC59 leucine rich repeat containing 59
LTF lactotransferrin
MCM10 minichromosome maintenance complex component 10
NME1 NME/NM23 nucleoside diphosphate kinase 1
NTS neurotensin
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PHGDH phosphoglycerate dehydrogenase
PITX1 paired-like homeodomain 1
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PPIF peptidylprolyl isomerase F
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPS1 phosphoribosyl pyrophosphate synthetase 1
RAD51C RAD51 paralog C
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SHCBP1 SHC SH2-domain binding protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
SUB1 SUB1 homolog (S. cerevisiae)
TIPIN TIMELESS interacting protein
TRBC1 T cell receptor beta constant 1
TRIP13 thyroid hormone receptor interactor 13
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S