BRD-A18328003_GDC-0980_HS578T_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

154 genes differentially expressed following the BRD-A18328003_GDC-0980_HS578T_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP9 A kinase (PRKA) anchor protein 9
AMDHD2 amidohydrolase domain containing 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD36B ankyrin repeat domain 36B
AREG amphiregulin
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CHN2 chimerin 2
CIRBP cold inducible RNA binding protein
CLDN8 claudin 8
COL4A5 collagen, type IV, alpha 5
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
DEPTOR DEP domain containing MTOR-interacting protein
DSP desmoplakin
DST dystonin
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM171A1 family with sequence similarity 171, member A1
FAM8A1 family with sequence similarity 8, member A1
FGF13 fibroblast growth factor 13
FHL1 four and a half LIM domains 1
FNBP1 formin binding protein 1
FOXO4 forkhead box O4
FZD7 frizzled class receptor 7
GAA glucosidase, alpha; acid
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRN granulin
GSN gelsolin
HECA headcase homolog (Drosophila)
HLA-E major histocompatibility complex, class I, E
HMGA2 high mobility group AT-hook 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFITM1 interferon induced transmembrane protein 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IQCG IQ motif containing G
IRS1 insulin receptor substrate 1
ITM2A integral membrane protein 2A
KLHL24 kelch-like family member 24
LINC00341 long intergenic non-protein coding RNA 341
LTBP1 latent transforming growth factor beta binding protein 1
LY75 lymphocyte antigen 75
MAGEB2 melanoma antigen family B2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MXRA7 matrix-remodelling associated 7
N4BP2L2 NEDD4 binding protein 2-like 2
NKTR natural killer cell triggering receptor
NOTCH2NL notch 2 N-terminal like
NT5E 5'-nucleotidase, ecto (CD73)
OPTN optineurin
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PERP PERP, TP53 apoptosis effector
PHYH phytanoyl-CoA 2-hydroxylase
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PILRB paired immunoglobin-like type 2 receptor beta
PRKCQ protein kinase C, theta
PTCH1 patched 1
RAB40B RAB40B, member RAS oncogene family
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB2 SATB homeobox 2
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SSFA2 sperm specific antigen 2
SYNE2 spectrin repeat containing, nuclear envelope 2
TFF1 trefoil factor 1
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TJP2 tight junction protein 2
TSC22D1 TSC22 domain family, member 1
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor
VCAN versican
VNN1 vanin 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZNF277 zinc finger protein 277
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AK2 adenylate kinase 2
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDOA aldolase A, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD38 CD38 molecule
CENPU centromere protein U
CNN3 calponin 3, acidic
COTL1 coactosin-like F-actin binding protein 1
CTPS1 CTP synthase 1
CYCS cytochrome c, somatic
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENO1 enolase 1, (alpha)
FADS1 fatty acid desaturase 1
FOLR1 folate receptor 1 (adult)
GALE UDP-galactose-4-epimerase
GARS glycyl-tRNA synthetase
GINS1 GINS complex subunit 1 (Psf1 homolog)
H2AFZ H2A histone family, member Z
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ISL1 ISL LIM homeobox 1
KRT4 keratin 4, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LRRC59 leucine rich repeat containing 59
MARS methionyl-tRNA synthetase
MCM2 minichromosome maintenance complex component 2
MCM5 minichromosome maintenance complex component 5
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMT1 N-myristoyltransferase 1
NRIP1 nuclear receptor interacting protein 1
PCNA proliferating cell nuclear antigen
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGAM1 phosphoglycerate mutase 1 (brain)
PGC progastricsin (pepsinogen C)
PHB prohibitin
PHGDH phosphoglycerate dehydrogenase
PLAC8 placenta-specific 8
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNP purine nucleoside phosphorylase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRMT1 protein arginine methyltransferase 1
PSAT1 phosphoserine aminotransferase 1
PVALB parvalbumin
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
TARS threonyl-tRNA synthetase
TIMELESS timeless circadian clock
TUBG1 tubulin, gamma 1
TYMS thymidylate synthetase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A
YARS tyrosyl-tRNA synthetase
ZWINT ZW10 interacting kinetochore protein