BRD-A18328003_GDC-0980_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the BRD-A18328003_GDC-0980_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRF5 adhesion G protein-coupled receptor F5
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD36B ankyrin repeat domain 36B
ANXA4 annexin A4
ATF4 activating transcription factor 4
ATP10A ATPase, class V, type 10A
ATP9A ATPase, class II, type 9A
BBX bobby sox homolog (Drosophila)
BCL6 B-cell CLL/lymphoma 6
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BPTF bromodomain PHD finger transcription factor
CCDC68 coiled-coil domain containing 68
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC2B C-type lectin domain family 2, member B
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CST1 cystatin SN
CTGF connective tissue growth factor
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EFNA1 ephrin-A1
ENG endoglin
EPAS1 endothelial PAS domain protein 1
ERBB3 erb-b2 receptor tyrosine kinase 3
FOXO4 forkhead box O4
FST follistatin
GAB2 GRB2-associated binding protein 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATA2 GATA binding protein 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
HDGFRP3 hepatoma-derived growth factor, related protein 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGFBP1 insulin-like growth factor binding protein 1
INHBA inhibin, beta A
IRS2 insulin receptor substrate 2
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
JUP junction plakoglobin
KLF9 Kruppel-like factor 9
KRT18 keratin 18, type I
LEPROT leptin receptor overlapping transcript
LGALS8 lectin, galactoside-binding, soluble, 8
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LUC7L3 LUC7-like 3 (S. cerevisiae)
MACF1 microtubule-actin crosslinking factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MN1 meningioma (disrupted in balanced translocation) 1
MPDZ multiple PDZ domain protein
MTSS1 metastasis suppressor 1
NDRG1 N-myc downstream regulated 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
OPTN optineurin
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDLIM5 PDZ and LIM domain 5
PFKL phosphofructokinase, liver
PLCB4 phospholipase C, beta 4
PRAME preferentially expressed antigen in melanoma
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXDC1 PX domain containing 1
PXDN peroxidasin
RAP2A RAP2A, member of RAS oncogene family
RB1CC1 RB1-inducible coiled-coil 1
RBKS ribokinase
RBP4 retinol binding protein 4, plasma
RIOK3 RIO kinase 3
S100P S100 calcium binding protein P
SLC38A2 solute carrier family 38, member 2
SULF1 sulfatase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TAL1 T-cell acute lymphocytic leukemia 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TM4SF4 transmembrane 4 L six family member 4
TNS3 tensin 3
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
VNN1 vanin 1
WT1 Wilms tumor 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTG2 actin, gamma 2, smooth muscle, enteric
AURKA aurora kinase A
BARD1 BRCA1 associated RING domain 1
BIRC5 baculoviral IAP repeat containing 5
BTG2 BTG family, member 2
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CCNA2 cyclin A2
CCND2 cyclin D2
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CENPU centromere protein U
CETN2 centrin, EF-hand protein, 2
CFD complement factor D (adipsin)
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CPVL carboxypeptidase, vitellogenic-like
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSTA cystatin A (stefin A)
DBF4 DBF4 zinc finger
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EBP emopamil binding protein (sterol isomerase)
ELOVL2 ELOVL fatty acid elongase 2
EMP3 epithelial membrane protein 3
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FANCG Fanconi anemia, complementation group G
FEN1 flap structure-specific endonuclease 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GMNN geminin, DNA replication inhibitor
H2AFX H2A histone family, member X
HAT1 histone acetyltransferase 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
JCHAIN joining chain of multimeric IgA and IgM
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LUM lumican
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MELK maternal embryonic leucine zipper kinase
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MSMO1 methylsterol monooxygenase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBPC1 myosin binding protein C, slow type
MYCBP MYC binding protein
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NES nestin
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POU2AF1 POU class 2 associating factor 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDX2 peroxiredoxin 2
PSPH phosphoserine phosphatase
PTN pleiotrophin
RFC3 replication factor C (activator 1) 3, 38kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RRM2 ribonucleotide reductase M2
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A7 S100 calcium binding protein A7
SFN stratifin
SLN sarcolipin
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
SUB1 SUB1 homolog (S. cerevisiae)
TIAM1 T-cell lymphoma invasion and metastasis 1
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZWINT ZW10 interacting kinetochore protein