BRD-A18328003_GDC-0980_HEPG2_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

169 genes differentially expressed following the BRD-A18328003_GDC-0980_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM10 ADAM metallopeptidase domain 10
ADAM28 ADAM metallopeptidase domain 28
AGTR1 angiotensin II receptor, type 1
AHNAK AHNAK nucleoprotein
AKAP12 A kinase (PRKA) anchor protein 12
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKRD36B ankyrin repeat domain 36B
APOD apolipoprotein D
ARID5B AT rich interactive domain 5B (MRF1-like)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEX4 brain expressed, X-linked 4
C10ORF10 chromosome 10 open reading frame 10
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLEC2B C-type lectin domain family 2, member B
CP ceruloplasmin (ferroxidase)
CST1 cystatin SN
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTGF connective tissue growth factor
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DARS aspartyl-tRNA synthetase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EPHA3 EPH receptor A3
ERBB3 erb-b2 receptor tyrosine kinase 3
FGB fibrinogen beta chain
FN1 fibronectin 1
FNBP1 formin binding protein 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FST follistatin
GAB2 GRB2-associated binding protein 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAS6 growth arrest-specific 6
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GPX3 glutathione peroxidase 3
HBP1 HMG-box transcription factor 1
HECA headcase homolog (Drosophila)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFBP1 insulin-like growth factor binding protein 1
IRS2 insulin receptor substrate 2
ITGA6 integrin, alpha 6
ITGB5 integrin, beta 5
JMJD1C jumonji domain containing 1C
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
KRT18 keratin 18, type I
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LEPR leptin receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
LRP10 low density lipoprotein receptor-related protein 10
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MARCKS myristoylated alanine-rich protein kinase C substrate
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL2 muscleblind-like splicing regulator 2
MFAP5 microfibrillar associated protein 5
MGLL monoglyceride lipase
MPDZ multiple PDZ domain protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5E 5'-nucleotidase, ecto (CD73)
OPTN optineurin
PDLIM5 PDZ and LIM domain 5
PDZK1IP1 PDZK1 interacting protein 1
PLAT plasminogen activator, tissue
PPAP2C phosphatidic acid phosphatase type 2C
PXDN peroxidasin
QPCT glutaminyl-peptide cyclotransferase
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGCC regulator of cell cycle
RUNX3 runt-related transcription factor 3
SATB1 SATB homeobox 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
TWF2 twinfilin actin binding protein 2
WNK1 WNK lysine deficient protein kinase 1
WT1 Wilms tumor 1
YPEL5 yippee-like 5 (Drosophila)
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACTA2 actin, alpha 2, smooth muscle, aorta
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CETN2 centrin, EF-hand protein, 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
COL3A1 collagen, type III, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DSCC1 DNA replication and sister chromatid cohesion 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EBP emopamil binding protein (sterol isomerase)
EREG epiregulin
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FEN1 flap structure-specific endonuclease 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GJA1 gap junction protein, alpha 1, 43kDa
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GRWD1 glutamate-rich WD repeat containing 1
GTSE1 G-2 and S-phase expressed 1
HILPDA hypoxia inducible lipid droplet-associated
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP5 insulin-like growth factor binding protein 5
JCHAIN joining chain of multimeric IgA and IgM
KIF20A kinesin family member 20A
LMNB1 lamin B1
LUM lumican
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MCM10 minichromosome maintenance complex component 10
MSMO1 methylsterol monooxygenase 1
MT1E metallothionein 1E
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY neuropeptide Y
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OIP5 Opa interacting protein 5
PBK PDZ binding kinase
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLK1 polo-like kinase 1
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POSTN periostin, osteoblast specific factor
PRDX2 peroxiredoxin 2
RAD23B RAD23 homolog B (S. cerevisiae)
RFC3 replication factor C (activator 1) 3, 38kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
SESN1 sestrin 1
SFTPB surfactant protein B
SLN sarcolipin
SORD sorbitol dehydrogenase
SPARCL1 SPARC-like 1 (hevin)
SQLE squalene epoxidase
TMEM14A transmembrane protein 14A
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPO thymopoietin
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C
ZDHHC6 zinc finger, DHHC-type containing 6
ZWINT ZW10 interacting kinetochore protein