BRD-A18328003_GDC-0980_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

216 genes differentially expressed following the BRD-A18328003_GDC-0980_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
AOX1 aldehyde oxidase 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASMTL acetylserotonin O-methyltransferase-like
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP9A ATPase, class II, type 9A
BCL6 B-cell CLL/lymphoma 6
BTG1 B-cell translocation gene 1, anti-proliferative
C1ORF115 chromosome 1 open reading frame 115
C6ORF48 chromosome 6 open reading frame 48
C9ORF16 chromosome 9 open reading frame 16
C9ORF3 chromosome 9 open reading frame 3
CAMLG calcium modulating ligand
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL4 chemokine (C-C motif) ligand 4
CD14 CD14 molecule
CES1 carboxylesterase 1
CFB complement factor B
CHRDL1 chordin-like 1
CLU clusterin
CRIP1 cysteine-rich protein 1 (intestinal)
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSTB cystatin B (stefin B)
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTSF cathepsin F
DIAPH2 diaphanous-related formin 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
EIF4B eukaryotic translation initiation factor 4B
FAIM Fas apoptotic inhibitory molecule
FAM134A family with sequence similarity 134, member A
FAM63A family with sequence similarity 63, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXO4 forkhead box O4
FTH1 ferritin, heavy polypeptide 1
GABARAP GABA(A) receptor-associated protein
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUL glutamate-ammonia ligase
GOLGA8H golgin A8 family, member H
GRN granulin
GSN gelsolin
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFI27 interferon, alpha-inducible protein 27
IFITM2 interferon induced transmembrane protein 2
IGBP1 immunoglobulin (CD79A) binding protein 1
IGFBP7 insulin-like growth factor binding protein 7
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
JUP junction plakoglobin
KLHL24 kelch-like family member 24
LAMB2 laminin, beta 2 (laminin S)
LETMD1 LETM1 domain containing 1
LGALS8 lectin, galactoside-binding, soluble, 8
LOC399491
LTA4H leukotriene A4 hydrolase
LTBP2 latent transforming growth factor beta binding protein 2
MAGED2 melanoma antigen family D2
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MMP9 matrix metallopeptidase 9
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MXRA7 matrix-remodelling associated 7
MYLK myosin light chain kinase
MZF1 myeloid zinc finger 1
NUMA1 nuclear mitotic apparatus protein 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFC platelet derived growth factor C
PENK proenkephalin
PGLS 6-phosphogluconolactonase
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
PLSCR3 phospholipid scramblase 3
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPL periplakin
QARS glutaminyl-tRNA synthetase
RALGDS ral guanine nucleotide dissociation stimulator
RAP1GAP RAP1 GTPase activating protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RNASE4 ribonuclease, RNase A family, 4
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1D2 secretoglobin, family 1D, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH3BP4 SH3-domain binding protein 4
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIDT2 SID1 transmembrane family, member 2
SLC38A2 solute carrier family 38, member 2
SMAD3 SMAD family member 3
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TACSTD2 tumor-associated calcium signal transducer 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
TP53I3 tumor protein p53 inducible protein 3
TPP1 tripeptidyl peptidase I
TRIM22 tripartite motif containing 22
TRIM8 tripartite motif containing 8
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
TSPAN4 tetraspanin 4
TXNIP thioredoxin interacting protein
WDR13 WD repeat domain 13
WDR19 WD repeat domain 19
WDR45 WD repeat domain 45

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AK4 adenylate kinase 4
AKAP12 A kinase (PRKA) anchor protein 12
ARL4C ADP-ribosylation factor-like 4C
ASF1B anti-silencing function 1B histone chaperone
ATAD2 ATPase family, AAA domain containing 2
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CENPU centromere protein U
CNN3 calponin 3, acidic
COX11 COX11 cytochrome c oxidase copper chaperone
CTPS1 CTP synthase 1
DDIT4 DNA-damage-inducible transcript 4
DHFR dihydrofolate reductase
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENOPH1 enolase-phosphatase 1
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FAM129A family with sequence similarity 129, member A
FEN1 flap structure-specific endonuclease 1
FOSL1 FOS-like antigen 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GOLM1 golgi membrane protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HACD3 3-hydroxyacyl-CoA dehydratase 3
HELLS helicase, lymphoid-specific
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HOXB7 homeobox B7
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LTF lactotransferrin
MALL mal, T-cell differentiation protein-like
MCM10 minichromosome maintenance complex component 10
MCM4 minichromosome maintenance complex component 4
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MELK maternal embryonic leucine zipper kinase
MOCOS molybdenum cofactor sulfurase
MRPL12 mitochondrial ribosomal protein L12
MRPS16 mitochondrial ribosomal protein S16
MRPS28 mitochondrial ribosomal protein S28
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NDC1 NDC1 transmembrane nucleoporin
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
PDE4B phosphodiesterase 4B, cAMP-specific
PHB prohibitin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIF peptidylprolyl isomerase F
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPF4 pre-mRNA processing factor 4
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PSPH phosphoserine phosphatase
RAD51 RAD51 recombinase
RCAN1 regulator of calcineurin 1
RFC2 replication factor C (activator 1) 2, 40kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS2 regulator of G-protein signaling 2
RRM2 ribonucleotide reductase M2
RTN1 reticulon 1
SCG2 secretogranin II
SDC1 syndecan 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHCBP1 SHC SH2-domain binding protein 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
STRA13 stimulated by retinoic acid 13
TFRC transferrin receptor
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMELESS timeless circadian clock
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TIPIN TIMELESS interacting protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
TNIK TRAF2 and NCK interacting kinase
TPM4 tropomyosin 4
TUBG1 tubulin, gamma 1
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
VRK1 vaccinia related kinase 1
ZWINT ZW10 interacting kinetochore protein