BRD-A18328003_GDC-0980_HA1E_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A18328003_GDC-0980_HA1E_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL5 chemokine (C-C motif) ligand 5
CDCA4 cell division cycle associated 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLC Charcot-Leyden crystal galectin
CST3 cystatin C
CST7 cystatin F (leukocystatin)
DENND2D DENN/MADD domain containing 2D
EDN1 endothelin 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFITM1 interferon induced transmembrane protein 1
IRS2 insulin receptor substrate 2
MTUS1 microtubule associated tumor suppressor 1
NKG7 natural killer cell granule protein 7
POSTN periostin, osteoblast specific factor
SPRY2 sprouty homolog 2 (Drosophila)
SULF1 sulfatase 1
SYNE2 spectrin repeat containing, nuclear envelope 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT9 acyl-CoA thioesterase 9
ARG2 arginase 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CRYAB crystallin, alpha B
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
ELF5 E74-like factor 5 (ets domain transcription factor)
FRZB frizzled-related protein
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGFBP3 insulin-like growth factor binding protein 3
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LPL lipoprotein lipase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NPR3 natriuretic peptide receptor 3
PAX8 paired box 8
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PGM1 phosphoglucomutase 1
PLTP phospholipid transfer protein
PRDX4 peroxiredoxin 4
PRKCA protein kinase C, alpha
QPRT quinolinate phosphoribosyltransferase
S100A2 S100 calcium binding protein A2
SAP30 Sin3A-associated protein, 30kDa
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5