BRD-A18328003_GDC-0980_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM28 ADAM metallopeptidase domain 28
ADD3 adducin 3 (gamma)
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
ARID5B AT rich interactive domain 5B (MRF1-like)
CCNG1 cyclin G1
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLCN3 chloride channel, voltage-sensitive 3
CXCL3 chemokine (C-X-C motif) ligand 3
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
METTL7A methyltransferase like 7A
MYB v-myb avian myeloblastosis viral oncogene homolog
NID2 nidogen 2 (osteonidogen)
NUPR1 nuclear protein, transcriptional regulator, 1
OSR2 odd-skipped related transciption factor 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PELI1 pellino E3 ubiquitin protein ligase 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
SEPP1 selenoprotein P, plasma, 1
SYT1 synaptotagmin I
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR2 early growth response 2
EIF4A1 eukaryotic translation initiation factor 4A1
G0S2 G0/G1 switch 2
JUN jun proto-oncogene
KRT17 keratin 17, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRP1 neuropilin 1
S100A10 S100 calcium binding protein A10
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SPP1 secreted phosphoprotein 1
SRGN serglycin
TFF1 trefoil factor 1