BRD-A18328003_GDC-0980_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
APLP2 amyloid beta (A4) precursor-like protein 2
APOD apolipoprotein D
ARID5B AT rich interactive domain 5B (MRF1-like)
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD99 CD99 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHIC2 cysteine-rich hydrophobic domain 2
CPE carboxypeptidase E
ELOVL5 ELOVL fatty acid elongase 5
ERBB3 erb-b2 receptor tyrosine kinase 3
FOXN3 forkhead box N3
GATA3 GATA binding protein 3
GLUL glutamate-ammonia ligase
GSTM3 glutathione S-transferase mu 3 (brain)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HECA headcase homolog (Drosophila)
HOXC6 homeobox C6
IGFBP5 insulin-like growth factor binding protein 5
IRS2 insulin receptor substrate 2
KIAA0355 KIAA0355
KLF9 Kruppel-like factor 9
KLHDC2 kelch domain containing 2
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MTUS1 microtubule associated tumor suppressor 1
NBR1 neighbor of BRCA1 gene 1
NDFIP1 Nedd4 family interacting protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PALMD palmdelphin
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
REXO2 RNA exonuclease 2
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SESN1 sestrin 1
SOD2 superoxide dismutase 2, mitochondrial
TIMP3 TIMP metallopeptidase inhibitor 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCL13 chemokine (C-X-C motif) ligand 13
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EFNB2 ephrin-B2
EPHA2 EPH receptor A2
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GATA2 GATA binding protein 2
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
JMJD6 jumonji domain containing 6
MAT2A methionine adenosyltransferase II, alpha
MYC v-myc avian myelocytomatosis viral oncogene homolog
NQO1 NAD(P)H dehydrogenase, quinone 1
NXT1 nuclear transport factor 2-like export factor 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
PNP purine nucleoside phosphorylase
RBP1 retinol binding protein 1, cellular
RGS3 regulator of G-protein signaling 3
SDC4 syndecan 4
SFN stratifin
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD7 SMAD family member 7
TNC tenascin C