BRD-A18328003_GDC-0980_BT20_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
AHR aryl hydrocarbon receptor
APOD apolipoprotein D
CCL4 chemokine (C-C motif) ligand 4
CD300A CD300a molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CNPY3 canopy FGF signaling regulator 3
COL11A1 collagen, type XI, alpha 1
CYTIP cytohesin 1 interacting protein
DPP4 dipeptidyl-peptidase 4
EPCAM epithelial cell adhesion molecule
EPHA3 EPH receptor A3
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
GPR183 G protein-coupled receptor 183
GRB7 growth factor receptor-bound protein 7
KLHL24 kelch-like family member 24
KRT19 keratin 19, type I
MGP matrix Gla protein
NID2 nidogen 2 (osteonidogen)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
RGS1 regulator of G-protein signaling 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SESN1 sestrin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VAV3 vav 3 guanine nucleotide exchange factor
XCL1 chemokine (C motif) ligand 1

decreased expression

Symbol Name
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATF5 activating transcription factor 5
BASP1 brain abundant, membrane attached signal protein 1
CA2 carbonic anhydrase II
CDC25A cell division cycle 25A
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFNB2 ephrin-B2
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FOSL1 FOS-like antigen 1
GCH1 GTP cyclohydrolase 1
GNAS GNAS complex locus
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX2 glutathione peroxidase 2
HBEGF heparin-binding EGF-like growth factor
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITGA6 integrin, alpha 6
KLF10 Kruppel-like factor 10
MAT2A methionine adenosyltransferase II, alpha
NELL2 NEL-like 2 (chicken)
NRG1 neuregulin 1
ODC1 ornithine decarboxylase 1
OLFM4 olfactomedin 4
PNP purine nucleoside phosphorylase
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SIK1 salt-inducible kinase 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
VIM vimentin