BRD-A18328003_GDC-0980_BT20_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

187 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARID5B AT rich interactive domain 5B (MRF1-like)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP9A ATPase, class II, type 9A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
C14ORF132 chromosome 14 open reading frame 132
CAMLG calcium modulating ligand
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CETN3 centrin, EF-hand protein, 3
CFB complement factor B
CLEC2B C-type lectin domain family 2, member B
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTSB cathepsin B
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDAH2 dimethylarginine dimethylaminohydrolase 2
ECHDC2 enoyl CoA hydratase domain containing 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
EXPH5 exophilin 5
FOXN3 forkhead box N3
FOXO4 forkhead box O4
GAB2 GRB2-associated binding protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GBP2 guanylate binding protein 2, interferon-inducible
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GPR137B G protein-coupled receptor 137B
HBP1 HMG-box transcription factor 1
HECA headcase homolog (Drosophila)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
IFITM1 interferon induced transmembrane protein 1
IL1R1 interleukin 1 receptor, type I
KDM3A lysine (K)-specific demethylase 3A
KDM5B lysine (K)-specific demethylase 5B
KDM5D lysine (K)-specific demethylase 5D
KLF9 Kruppel-like factor 9
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
KRT15 keratin 15, type I
LEPR leptin receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00341 long intergenic non-protein coding RNA 341
LRP10 low density lipoprotein receptor-related protein 10
LUM lumican
LYRM1 LYR motif containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN2A1 mannosidase, alpha, class 2A, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
METTL7A methyltransferase like 7A
MMP9 matrix metallopeptidase 9
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MXI1 MAX interactor 1, dimerization protein
MYO6 myosin VI
NAV2 neuron navigator 2
NBR1 neighbor of BRCA1 gene 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPAP2B phosphatidic acid phosphatase type 2B
QPCT glutaminyl-peptide cyclotransferase
RAB31 RAB31, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RB1CC1 RB1-inducible coiled-coil 1
RGS5 regulator of G-protein signaling 5
RNF103 ring finger protein 103
SAT1 spermidine/spermine N1-acetyltransferase 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
SOX4 SRY (sex determining region Y)-box 4
STON1 stonin 1
TBX3 T-box 3
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TNS1 tensin 1
TPBG trophoblast glycoprotein
TRPS1 trichorhinophalangeal syndrome I
TXNIP thioredoxin interacting protein
WDTC1 WD and tetratricopeptide repeats 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANXA3 annexin A3
ASPH aspartate beta-hydroxylase
ATF5 activating transcription factor 5
ATG3 autophagy related 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BANF1 barrier to autointegration factor 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BZW2 basic leucine zipper and W2 domains 2
C1QBP complement component 1, q subcomponent binding protein
CAV2 caveolin 2
CBR3 carbonyl reductase 3
CD36 CD36 molecule (thrombospondin receptor)
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CDK4 cyclin-dependent kinase 4
CENPU centromere protein U
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CKS1B CDC28 protein kinase regulatory subunit 1B
COTL1 coactosin-like F-actin binding protein 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFNB2 ephrin-B2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
ENO1 enolase 1, (alpha)
ENOPH1 enolase-phosphatase 1
FADS1 fatty acid desaturase 1
FAM57A family with sequence similarity 57, member A
FEN1 flap structure-specific endonuclease 1
FGFR2 fibroblast growth factor receptor 2
FOSL1 FOS-like antigen 1
GGCT gamma-glutamylcyclotransferase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HN1 hematological and neurological expressed 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ITGB1BP1 integrin beta 1 binding protein 1
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC59 leucine rich repeat containing 59
MAK16 MAK16 homolog (S. cerevisiae)
MCM3 minichromosome maintenance complex component 3
MLEC malectin
MMP12 matrix metallopeptidase 12
MRPL12 mitochondrial ribosomal protein L12
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPR3 natriuretic peptide receptor 3
NRIP1 nuclear receptor interacting protein 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PFN2 profilin 2
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PKM pyruvate kinase, muscle
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPARG peroxisome proliferator-activated receptor gamma
PPIF peptidylprolyl isomerase F
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PYCR1 pyrroline-5-carboxylate reductase 1
RAD51C RAD51 paralog C
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SMC1A structural maintenance of chromosomes 1A
SNX10 sorting nexin 10
STRA13 stimulated by retinoic acid 13
TFRC transferrin receptor
TMEM109 transmembrane protein 109
TOX3 TOX high mobility group box family member 3
TPM1 tropomyosin 1 (alpha)
TUBB tubulin, beta class I
TYMS thymidylate synthetase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE3C ubiquitin protein ligase E3C
XIST X inactive specific transcript (non-protein coding)
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZWINT ZW10 interacting kinetochore protein