BRD-A18328003_GDC-0980_BT20_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

133 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AUH AU RNA binding protein/enoyl-CoA hydratase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL6 B-cell CLL/lymphoma 6
C10ORF10 chromosome 10 open reading frame 10
C6ORF62 chromosome 6 open reading frame 62
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CD46 CD46 molecule, complement regulatory protein
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DSP desmoplakin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EXPH5 exophilin 5
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXN3 forkhead box N3
GABARAPL2 GABA(A) receptor-associated protein-like 2
GCC2 GRIP and coiled-coil domain containing 2
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUL glutamate-ammonia ligase
HBP1 HMG-box transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HMOX1 heme oxygenase 1
IRS2 insulin receptor substrate 2
ISCU iron-sulfur cluster assembly enzyme
KIAA1033 KIAA1033
KLF9 Kruppel-like factor 9
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
LBH limb bud and heart development
LGALS8 lectin, galactoside-binding, soluble, 8
LRP10 low density lipoprotein receptor-related protein 10
LUM lumican
LXN latexin
MSMB microseminoprotein, beta-
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MXI1 MAX interactor 1, dimerization protein
MYLIP myosin regulatory light chain interacting protein
MYLK myosin light chain kinase
NBR1 neighbor of BRCA1 gene 1
NEBL nebulette
PDGFD platelet derived growth factor D
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP prolactin-induced protein
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLIN2 perilipin 2
PNRC1 proline-rich nuclear receptor coactivator 1
RB1CC1 RB1-inducible coiled-coil 1
RGS10 regulator of G-protein signaling 10
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SLC38A2 solute carrier family 38, member 2
SOS2 son of sevenless homolog 2 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
TBX3 T-box 3
TGIF1 TGFB-induced factor homeobox 1
TMEM59 transmembrane protein 59
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP1 TNFAIP3 interacting protein 1
TNS3 tensin 3
TOB1 transducer of ERBB2, 1
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CALU calumenin
CAV2 caveolin 2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CIAPIN1 cytokine induced apoptosis inhibitor 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYB561 cytochrome b561
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFNB2 ephrin-B2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
ENO1 enolase 1, (alpha)
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GALE UDP-galactose-4-epimerase
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GSTM3 glutathione S-transferase mu 3 (brain)
HBEGF heparin-binding EGF-like growth factor
HN1 hematological and neurological expressed 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
KCTD12 potassium channel tetramerization domain containing 12
MCM3 minichromosome maintenance complex component 3
MLF1 myeloid leukemia factor 1
MRPL12 mitochondrial ribosomal protein L12
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
ODC1 ornithine decarboxylase 1
OLFM4 olfactomedin 4
PFN2 profilin 2
PGM1 phosphoglucomutase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNP purine nucleoside phosphorylase
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRMT1 protein arginine methyltransferase 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RFC4 replication factor C (activator 1) 4, 37kDa
RRM2 ribonucleotide reductase M2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
SPINK1 serine peptidase inhibitor, Kazal type 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TUBB6 tubulin, beta 6 class V
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1