BRD-A18328003_GDC-0980_BT20_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

180 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
AES amino-terminal enhancer of split
AKAP13 A kinase (PRKA) anchor protein 13
ANKRD36B ankyrin repeat domain 36B
ATP9A ATPase, class II, type 9A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACE2 beta-site APP-cleaving enzyme 2
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
C6ORF62 chromosome 6 open reading frame 62
CBX7 chromobox homolog 7
CCNG2 cyclin G2
CD59 CD59 molecule, complement regulatory protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CP ceruloplasmin (ferroxidase)
CREBL2 cAMP responsive element binding protein-like 2
CRISP3 cysteine-rich secretory protein 3
CST1 cystatin SN
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTSS cathepsin S
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYTH1 cytohesin 1
DST dystonin
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
FGG fibrinogen gamma chain
FOXN3 forkhead box N3
FOXO4 forkhead box O4
GAA glucosidase, alpha; acid
GAS6 growth arrest-specific 6
GBP2 guanylate binding protein 2, interferon-inducible
GLUL glutamate-ammonia ligase
GPR137B G protein-coupled receptor 137B
GRN granulin
HBP1 HMG-box transcription factor 1
HECA headcase homolog (Drosophila)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
IL6ST interleukin 6 signal transducer
ITM2B integral membrane protein 2B
JUP junction plakoglobin
KDM3A lysine (K)-specific demethylase 3A
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
LBH limb bud and heart development
LOC100272216 uncharacterized LOC100272216
LRP10 low density lipoprotein receptor-related protein 10
LXN latexin
MAN2B1 mannosidase, alpha, class 2B, member 1
MCL1 myeloid cell leukemia 1
METTL7A methyltransferase like 7A
MMP9 matrix metallopeptidase 9
MT1F metallothionein 1F
MT1X metallothionein 1X
MVP major vault protein
MXI1 MAX interactor 1, dimerization protein
N4BP2L1 NEDD4 binding protein 2-like 1
NBR1 neighbor of BRCA1 gene 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB31 RAB31, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC46A3 solute carrier family 46, member 3
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLE2 transducin-like enhancer of split 2
TMEM59 transmembrane protein 59
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
TPP1 tripeptidyl peptidase I
TRIM22 tripartite motif containing 22
TSPAN6 tetraspanin 6
TXNIP thioredoxin interacting protein
WDTC1 WD and tetratricopeptide repeats 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AK4 adenylate kinase 4
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA3 annexin A3
AREG amphiregulin
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BZW2 basic leucine zipper and W2 domains 2
C3ORF14 chromosome 3 open reading frame 14
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDC6 cell division cycle 6
CDK4 cyclin-dependent kinase 4
CKAP4 cytoskeleton-associated protein 4
COL14A1 collagen, type XIV, alpha 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTPS1 CTP synthase 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYCS cytochrome c, somatic
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DPT dermatopontin
EBP emopamil binding protein (sterol isomerase)
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5 eukaryotic translation initiation factor 5
ELOVL6 ELOVL fatty acid elongase 6
ENOPH1 enolase-phosphatase 1
FAM57A family with sequence similarity 57, member A
FBLN1 fibulin 1
FEN1 flap structure-specific endonuclease 1
GSTM3 glutathione S-transferase mu 3 (brain)
HSPA8 heat shock 70kDa protein 8
IGF1 insulin-like growth factor 1 (somatomedin C)
IRAK1 interleukin-1 receptor-associated kinase 1
KCTD12 potassium channel tetramerization domain containing 12
KRT6B keratin 6B, type II
L1CAM L1 cell adhesion molecule
LAGE3 L antigen family, member 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOC100505650 uncharacterized LOC100505650
LPL lipoprotein lipase
LTF lactotransferrin
MCM3 minichromosome maintenance complex component 3
MCM6 minichromosome maintenance complex component 6
MCUR1 mitochondrial calcium uniporter regulator 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPM3 nucleophosmin/nucleoplasmin 3
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
NRIP1 nuclear receptor interacting protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCNA proliferating cell nuclear antigen
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PEA15 phosphoprotein enriched in astrocytes 15
PEG10 paternally expressed 10
PGM1 phosphoglucomutase 1
PLAGL1 pleiomorphic adenoma gene-like 1
PMP22 peripheral myelin protein 22
PNP purine nucleoside phosphorylase
PPARG peroxisome proliferator-activated receptor gamma
PPIF peptidylprolyl isomerase F
PRMT1 protein arginine methyltransferase 1
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PYCR1 pyrroline-5-carboxylate reductase 1
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RFC3 replication factor C (activator 1) 3, 38kDa
S100A6 S100 calcium binding protein A6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEH1L SEH1-like (S. cerevisiae)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SRM spermidine synthase
SRP72 signal recognition particle 72kDa
SRPX sushi-repeat containing protein, X-linked
TFRC transferrin receptor
TPM1 tropomyosin 1 (alpha)
TRIP13 thyroid hormone receptor interactor 13
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TYMS thymidylate synthetase
WSB2 WD repeat and SOCS box containing 2
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZWINT ZW10 interacting kinetochore protein