BRD-A17883755_Lenalidomide_HCC515_24.0_h_177.6_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-A17883755_Lenalidomide_HCC515_24.0_h_177.6_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
C3 complement component 3
CDH3 cadherin 3, type 1, P-cadherin (placental)
EPCAM epithelial cell adhesion molecule
FKBP5 FK506 binding protein 5
GLUL glutamate-ammonia ligase
IGHM immunoglobulin heavy constant mu
LTF lactotransferrin
MAOA monoamine oxidase A
MUC1 mucin 1, cell surface associated
RHOB ras homolog family member B
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TSC22D3 TSC22 domain family, member 3
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ARL4C ADP-ribosylation factor-like 4C
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
CSRP1 cysteine and glycine-rich protein 1
GAP43 growth associated protein 43
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GNG11 guanine nucleotide binding protein (G protein), gamma 11
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KLK11 kallikrein-related peptidase 11
LYPD1 LY6/PLAUR domain containing 1
NPAS2 neuronal PAS domain protein 2
NTS neurotensin
PTN pleiotrophin
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SRGN serglycin
TPM1 tropomyosin 1 (alpha)
WT1 Wilms tumor 1