BRD-A17883755_Lenalidomide_A549_6.0_h_177.6_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

59 genes differentially expressed following the BRD-A17883755_Lenalidomide_A549_6.0_h_177.6_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
BCL6 B-cell CLL/lymphoma 6
C10ORF10 chromosome 10 open reading frame 10
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
EIF5A eukaryotic translation initiation factor 5A
EMP1 epithelial membrane protein 1
FKBP5 FK506 binding protein 5
GADD45B growth arrest and DNA-damage-inducible, beta
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KLF2 Kruppel-like factor 2
METTL7A methyltransferase like 7A
NCOA4 nuclear receptor coactivator 4
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PER1 period circadian clock 1
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
SFN stratifin
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TSC22D3 TSC22 domain family, member 3
VCAN versican
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
C1ORF106 chromosome 1 open reading frame 106
CCL2 chemokine (C-C motif) ligand 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
ERAP2 endoplasmic reticulum aminopeptidase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
GPM6B glycoprotein M6B
GSTM3 glutathione S-transferase mu 3 (brain)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP4 insulin-like growth factor binding protein 4
JUN jun proto-oncogene
LCN2 lipocalin 2
LXN latexin
MMP9 matrix metallopeptidase 9
NELL2 NEL-like 2 (chicken)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
TUBB2B tubulin, beta 2B class IIb
WT1 Wilms tumor 1