BRD-A17846016_Trolox_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-A17846016_Trolox_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCHE butyrylcholinesterase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CLEC2B C-type lectin domain family 2, member B
COL1A2 collagen, type I, alpha 2
DPYSL3 dihydropyrimidinase-like 3
FILIP1L filamin A interacting protein 1-like
FN1 fibronectin 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMG20B high mobility group 20B
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPG2 heparan sulfate proteoglycan 2
KLK10 kallikrein-related peptidase 10
LGALS1 lectin, galactoside-binding, soluble, 1
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MMP11 matrix metallopeptidase 11
NCAM1 neural cell adhesion molecule 1
NEFL neurofilament, light polypeptide
OLFML2A olfactomedin-like 2A
PDZRN3 PDZ domain containing ring finger 3
PLN phospholamban
PRUNE2 prune homolog 2 (Drosophila)
PTPRO protein tyrosine phosphatase, receptor type, O
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPON2 spondin 2, extracellular matrix protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRDV3 T cell receptor delta variable 3
VCAN versican
VIM vimentin

decreased expression

Symbol Name
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
BASP1 brain abundant, membrane attached signal protein 1
BST2 bone marrow stromal cell antigen 2
C1RL complement component 1, r subcomponent-like
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CBX1 chromobox homolog 1
CD59 CD59 molecule, complement regulatory protein
CENPA centromere protein A
CHPT1 choline phosphotransferase 1
CLU clusterin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLD dihydrolipoamide dehydrogenase
DPYSL2 dihydropyrimidinase-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM57A family with sequence similarity 57, member A
FXYD3 FXYD domain containing ion transport regulator 3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRSF1 G-rich RNA sequence binding factor 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEBP1 heme binding protein 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
KLF4 Kruppel-like factor 4 (gut)
KRT19 keratin 19, type I
KRT7 keratin 7, type II
KYNU kynureninase
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
NRIP1 nuclear receptor interacting protein 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
QDPR quinoid dihydropteridine reductase
RCAN1 regulator of calcineurin 1
REEP5 receptor accessory protein 5
S100A2 S100 calcium binding protein A2
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TJP2 tight junction protein 2
TM4SF1 transmembrane 4 L six family member 1
TSPAN13 tetraspanin 13
UBE3C ubiquitin protein ligase E3C