BRD-A17718497_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A17718497_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BEX1 brain expressed, X-linked 1
BTG1 B-cell translocation gene 1, anti-proliferative
CD163 CD163 molecule
CTGF connective tissue growth factor
CTSS cathepsin S
DDIT4 DNA-damage-inducible transcript 4
FAM107A family with sequence similarity 107, member A
FCGBP Fc fragment of IgG binding protein
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAS6 growth arrest-specific 6
GLUL glutamate-ammonia ligase
IFI27 interferon, alpha-inducible protein 27
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
METTL7A methyltransferase like 7A
MFAP2 microfibrillar-associated protein 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
OLFM4 olfactomedin 4
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDGFD platelet derived growth factor D
PLAU plasminogen activator, urokinase
PTX3 pentraxin 3, long
RAP1GAP RAP1 GTPase activating protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
SOX9 SRY (sex determining region Y)-box 9
SQSTM1 sequestosome 1
TMEM176B transmembrane protein 176B
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
VGLL1 vestigial-like family member 1
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
ACLY ATP citrate lyase
ARMT1 acidic residue methyltransferase 1
BAG3 BCL2-associated athanogene 3
DEGS1 delta(4)-desaturase, sphingolipid 1
EVL Enah/Vasp-like
FAM134B family with sequence similarity 134, member B
HSPB8 heat shock 22kDa protein 8
KIF14 kinesin family member 14
NKX3-1 NK3 homeobox 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
SFN stratifin
SMS spermine synthase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TNC tenascin C
TUBB6 tubulin, beta 6 class V
TXNDC9 thioredoxin domain containing 9