BRD-A17718497_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

62 genes differentially expressed following the BRD-A17718497_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATF3 activating transcription factor 3
CAPN2 calpain 2, (m/II) large subunit
CD9 CD9 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
DICER1 dicer 1, ribonuclease type III
EGR1 early growth response 1
FNDC3B fibronectin type III domain containing 3B
FOSL1 FOS-like antigen 1
FRMD4B FERM domain containing 4B
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
H1F0 H1 histone family, member 0
IER3 immediate early response 3
KIAA1598
KRT18 keratin 18, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PDGFA platelet-derived growth factor alpha polypeptide
RHOB ras homolog family member B
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
WSB1 WD repeat and SOCS box containing 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
APOD apolipoprotein D
ATF5 activating transcription factor 5
BASP1 brain abundant, membrane attached signal protein 1
CCNF cyclin F
CDC20 cell division cycle 20
CDKN2A cyclin-dependent kinase inhibitor 2A
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLGN calmegin
CRYAB crystallin, alpha B
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DMD dystrophin
FZD2 frizzled class receptor 2
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IGKV1-5 immunoglobulin kappa variable 1-5
KIF14 kinesin family member 14
L1CAM L1 cell adhesion molecule
PDZK1 PDZ domain containing 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PXMP2 peroxisomal membrane protein 2, 22kDa
RBKS ribokinase
RPS11 ribosomal protein S11
SESN1 sestrin 1
TFF1 trefoil factor 1
TM9SF2 transmembrane 9 superfamily member 2
TPBG trophoblast glycoprotein