BRD-A17535965_Gelsemine_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-A17535965_Gelsemine_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AQP9 aquaporin 9
ATP11B ATPase, class VI, type 11B
BEX1 brain expressed, X-linked 1
C10ORF10 chromosome 10 open reading frame 10
C5AR1 complement component 5a receptor 1
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CD52 CD52 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COG7 component of oligomeric golgi complex 7
COL4A5 collagen, type IV, alpha 5
COLEC12 collectin sub-family member 12
CPB1 carboxypeptidase B1 (tissue)
CYBB cytochrome b-245, beta polypeptide
DLK1 delta-like 1 homolog (Drosophila)
DPP4 dipeptidyl-peptidase 4
E2F2 E2F transcription factor 2
EGFL6 EGF-like-domain, multiple 6
FABP4 fatty acid binding protein 4, adipocyte
FLRT2 fibronectin leucine rich transmembrane protein 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCTD12 potassium channel tetramerization domain containing 12
LAPTM5 lysosomal protein transmembrane 5
LDOC1 leucine zipper, down-regulated in cancer 1
LINC00341 long intergenic non-protein coding RNA 341
LPAR6 lysophosphatidic acid receptor 6
MEIS2 Meis homeobox 2
NEB nebulin
NVL nuclear VCP-like
PAX5 paired box 5
PEG10 paternally expressed 10
PLXNC1 plexin C1
PRUNE2 prune homolog 2 (Drosophila)
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SHB Src homology 2 domain containing adaptor protein B
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SOX11 SRY (sex determining region Y)-box 11
STON1 stonin 1
TCEAL2 transcription elongation factor A (SII)-like 2
THBS1 thrombospondin 1
TRIM13 tripartite motif containing 13
VCAN versican

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BZW2 basic leucine zipper and W2 domains 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CHPT1 choline phosphotransferase 1
CLU clusterin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTSB cathepsin B
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GPX3 glutathione peroxidase 3
KRT10 keratin 10, type I
KRT16 keratin 16, type I
MCUR1 mitochondrial calcium uniporter regulator 1
MT1F metallothionein 1F
MT1X metallothionein 1X
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
PDLIM4 PDZ and LIM domain 4
RCAN1 regulator of calcineurin 1
SCAND1 SCAN domain containing 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SORD sorbitol dehydrogenase
SPRR1A small proline-rich protein 1A
TECR trans-2,3-enoyl-CoA reductase
TSPAN13 tetraspanin 13
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1