BRD-A17462676_Bambuterol hydrochloride_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

135 genes differentially expressed following the BRD-A17462676_Bambuterol hydrochloride_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C10ORF10 chromosome 10 open reading frame 10
DLK1 delta-like 1 homolog (Drosophila)
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
F13A1 coagulation factor XIII, A1 polypeptide
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HMGB3 high mobility group box 3
HOMER3 homer scaffolding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL1R2 interleukin 1 receptor, type II
IRF6 interferon regulatory factor 6
MEG3 maternally expressed 3 (non-protein coding)
MMP11 matrix metallopeptidase 11
NRGN neurogranin (protein kinase C substrate, RC3)
PLAU plasminogen activator, urokinase
PRSS3 protease, serine, 3
RAB2A RAB2A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBP1 retinol binding protein 1, cellular
S100A8 S100 calcium binding protein A8
SOX9 SRY (sex determining region Y)-box 9
SPON2 spondin 2, extracellular matrix protein
SPRR3 small proline-rich protein 3
SRSF5 serine/arginine-rich splicing factor 5
ST7 suppression of tumorigenicity 7
STAR steroidogenic acute regulatory protein
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2
TTN titin
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AGO3 argonaute RISC catalytic component 3
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP3 aquaporin 3 (Gill blood group)
ARMCX2 armadillo repeat containing, X-linked 2
ARMCX3 armadillo repeat containing, X-linked 3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BTG3 BTG family, member 3
C3ORF14 chromosome 3 open reading frame 14
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CBX1 chromobox homolog 1
CCND3 cyclin D3
CD24 CD24 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLIC5 chloride intracellular channel 5
CP ceruloplasmin (ferroxidase)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CXCL2 chemokine (C-X-C motif) ligand 2
DLD dihydrolipoamide dehydrogenase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
EBNA1BP2 EBNA1 binding protein 2
EED embryonic ectoderm development
EMP2 epithelial membrane protein 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM13B family with sequence similarity 13, member B
FAM46A family with sequence similarity 46, member A
FERMT2 fermitin family member 2
FOLR1 folate receptor 1 (adult)
G0S2 G0/G1 switch 2
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLS glutaminase
GNAS GNAS complex locus
GOLT1B golgi transport 1B
GPM6A glycoprotein M6A
GPX3 glutathione peroxidase 3
HOXD1 homeobox D1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF1R insulin-like growth factor 1 receptor
IRS1 insulin receptor substrate 1
ISG15 ISG15 ubiquitin-like modifier
ITGAV integrin, alpha V
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
IVNS1ABP influenza virus NS1A binding protein
KLF5 Kruppel-like factor 5 (intestinal)
KPNB1 karyopherin (importin) beta 1
KYNU kynureninase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARCKS myristoylated alanine-rich protein kinase C substrate
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MOAP1 modulator of apoptosis 1
MT1F metallothionein 1F
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
NKTR natural killer cell triggering receptor
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP62 nucleoporin 62kDa
OSBPL10 oxysterol binding protein-like 10
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG10 paternally expressed 10
PHF20 PHD finger protein 20
PNMAL1 paraneoplastic Ma antigen family-like 1
PRKCI protein kinase C, iota
PRPF4 pre-mRNA processing factor 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RPS27L ribosomal protein S27-like
RRP1B ribosomal RNA processing 1B
SAMD4A sterile alpha motif domain containing 4A
SAR1A secretion associated, Ras related GTPase 1A
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFN stratifin
SGCE sarcoglycan, epsilon
SGK1 serum/glucocorticoid regulated kinase 1
SLC38A1 solute carrier family 38, member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TOX3 TOX high mobility group box family member 3
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZMYM2 zinc finger, MYM-type 2
ZNF131 zinc finger protein 131