BRD-A17448384_beclomethasone_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

148 genes differentially expressed following the BRD-A17448384_beclomethasone_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM3 actin binding LIM protein family, member 3
ACSL1 acyl-CoA synthetase long-chain family member 1
AIM1 absent in melanoma 1
AKAP12 A kinase (PRKA) anchor protein 12
APOLD1 apolipoprotein L domain containing 1
AQP3 aquaporin 3 (Gill blood group)
ASS1 argininosuccinate synthase 1
BCL6 B-cell CLL/lymphoma 6
BGN biglycan
C10ORF10 chromosome 10 open reading frame 10
C1ORF116 chromosome 1 open reading frame 116
C8ORF4 chromosome 8 open reading frame 4
CALD1 caldesmon 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CES2 carboxylesterase 2
CFD complement factor D (adipsin)
CFH complement factor H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
DPP4 dipeptidyl-peptidase 4
DUSP1 dual specificity phosphatase 1
EMP2 epithelial membrane protein 2
EPN2 epsin 2
FAM134B family with sequence similarity 134, member B
FGFR4 fibroblast growth factor receptor 4
FKBP5 FK506 binding protein 5
FXYD6 FXYD domain containing ion transport regulator 6
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GLRX glutaredoxin (thioltransferase)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KAT6B K(lysine) acetyltransferase 6B
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT14 keratin 14, type I
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MSLN mesothelin
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOX4 NADPH oxidase 4
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM1 PDZ and LIM domain 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PER1 period circadian clock 1
PPL periplakin
PXDC1 PX domain containing 1
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
RHOB ras homolog family member B
S100A8 S100 calcium binding protein A8
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIK1 salt-inducible kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC38A1 solute carrier family 38, member 1
SNX7 sorting nexin 7
SYBU syntabulin (syntaxin-interacting)
TACC2 transforming, acidic coiled-coil containing protein 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
XIST X inactive specific transcript (non-protein coding)
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1

decreased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
BAD BCL2-associated agonist of cell death
CA1 carbonic anhydrase I
CBR3 carbonyl reductase 3
CCL2 chemokine (C-C motif) ligand 2
CCL8 chemokine (C-C motif) ligand 8
CLTC clathrin, heavy chain (Hc)
CLU clusterin
COCH cochlin
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DOCK10 dedicator of cytokinesis 10
DUSP14 dual specificity phosphatase 14
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
H1F0 H1 histone family, member 0
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HOXB6 homeobox B6
HOXB7 homeobox B7
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LMO2 LIM domain only 2 (rhombotin-like 1)
LPAR1 lysophosphatidic acid receptor 1
LTF lactotransferrin
MBNL2 muscleblind-like splicing regulator 2
MITF microphthalmia-associated transcription factor
MMP12 matrix metallopeptidase 12
NLRP2 NLR family, pyrin domain containing 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PENK proenkephalin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPIF peptidylprolyl isomerase F
PRNP prion protein
PROM1 prominin 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PXMP2 peroxisomal membrane protein 2, 22kDa
RALB v-ral simian leukemia viral oncogene homolog B
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
REEP5 receptor accessory protein 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPA3 replication protein A3, 14kDa
RPL37A ribosomal protein L37a
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SNAP25 synaptosomal-associated protein, 25kDa
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAB1 stabilin 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SYNJ2 synaptojanin 2
SYT1 synaptotagmin I
TFF3 trefoil factor 3 (intestinal)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TOX3 TOX high mobility group box family member 3
TPBG trophoblast glycoprotein
WT1 Wilms tumor 1
ZNF586 zinc finger protein 586