BRD-A17448384_beclomethasone_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A17448384_beclomethasone_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CASP2 caspase 2, apoptosis-related cysteine peptidase
E2F2 E2F transcription factor 2
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FASN fatty acid synthase
FGFR3 fibroblast growth factor receptor 3
GLUL glutamate-ammonia ligase
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
MAMLD1 mastermind-like domain containing 1
MYB v-myb avian myeloblastosis viral oncogene homolog
NELL2 NEL-like 2 (chicken)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
TESC tescalcin
TF transferrin
TFF3 trefoil factor 3 (intestinal)
TIMP3 TIMP metallopeptidase inhibitor 3

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
C1QB complement component 1, q subcomponent, B chain
CAST calpastatin
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CP ceruloplasmin (ferroxidase)
CYR61 cysteine-rich, angiogenic inducer, 61
DLD dihydrolipoamide dehydrogenase
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GJA1 gap junction protein, alpha 1, 43kDa
GLS glutaminase
GNAS GNAS complex locus
GNG10 guanine nucleotide binding protein (G protein), gamma 10
IER5 immediate early response 5
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KDM3A lysine (K)-specific demethylase 3A
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KYNU kynureninase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MCFD2 multiple coagulation factor deficiency 2
MCUR1 mitochondrial calcium uniporter regulator 1
MMP7 matrix metallopeptidase 7
PEG10 paternally expressed 10
PRNP prion protein
PRPF4 pre-mRNA processing factor 4
PTDSS1 phosphatidylserine synthase 1
RND3 Rho family GTPase 3
SDC2 syndecan 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM9SF3 transmembrane 9 superfamily member 3
TMEM45A transmembrane protein 45A
TPM4 tropomyosin 4
UFM1 ubiquitin-fold modifier 1
ZFAND1 zinc finger, AN1-type domain 1