BRD-A17428743_BW 723C86 hydrochloride_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-A17428743_BW 723C86 hydrochloride_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM2 absent in melanoma 2
APOD apolipoprotein D
C1ORF106 chromosome 1 open reading frame 106
CD44 CD44 molecule (Indian blood group)
CXCL12 chemokine (C-X-C motif) ligand 12
DUSP5 dual specificity phosphatase 5
KRT81 keratin 81, type II
RGS2 regulator of G-protein signaling 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD3 SMAD family member 3
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
CHN2 chimerin 2
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
FCGBP Fc fragment of IgG binding protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
KCTD12 potassium channel tetramerization domain containing 12
LCN2 lipocalin 2
LIMA1 LIM domain and actin binding 1
LIMCH1 LIM and calponin homology domains 1
RGCC regulator of cell cycle
SEPW1 selenoprotein W, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULF1 sulfatase 1