BRD-A17065207_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-A17065207_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
APOD apolipoprotein D
ARF4 ADP-ribosylation factor 4
ARHGAP29 Rho GTPase activating protein 29
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
CAB39 calcium binding protein 39
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COPA coatomer protein complex, subunit alpha
COPB1 coatomer protein complex, subunit beta 1
CREB3L2 cAMP responsive element binding protein 3-like 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FAM129A family with sequence similarity 129, member A
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP11 FK506 binding protein 11, 19 kDa
FTH1 ferritin, heavy polypeptide 1
GARS glycyl-tRNA synthetase
GFPT1 glutamine--fructose-6-phosphate transaminase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
INHBE inhibin, beta E
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LRRC17 leucine rich repeat containing 17
MANF mesencephalic astrocyte-derived neurotrophic factor
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYO10 myosin X
PDGFRL platelet-derived growth factor receptor-like
PSPH phosphoserine phosphatase
SARAF store-operated calcium entry-associated regulatory factor
SEC24D SEC24 family member D
SLC35B1 solute carrier family 35, member B1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SYT1 synaptotagmin I
TBL2 transducin (beta)-like 2
THBS2 thrombospondin 2
TMED2 transmembrane emp24 domain trafficking protein 2
TRAM1 translocation associated membrane protein 1
UFM1 ubiquitin-fold modifier 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AUTS2 autism susceptibility candidate 2
CA9 carbonic anhydrase IX
CD24 CD24 molecule
CDC42 cell division cycle 42
COL9A2 collagen, type IX, alpha 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYR61 cysteine-rich, angiogenic inducer, 61
EFNB2 ephrin-B2
ERBB2 erb-b2 receptor tyrosine kinase 2
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GLIPR1 GLI pathogenesis-related 1
GPX3 glutathione peroxidase 3
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IFRD2 interferon-related developmental regulator 2
IGFBP7 insulin-like growth factor binding protein 7
KAZN kazrin, periplakin interacting protein
KIF20A kinesin family member 20A
KLK10 kallikrein-related peptidase 10
KRT17 keratin 17, type I
MARCKSL1 MARCKS-like 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
PBX3 pre-B-cell leukemia homeobox 3
PDZK1IP1 PDZK1 interacting protein 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
PRKCI protein kinase C, iota
RHOB ras homolog family member B
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A10 S100 calcium binding protein A10
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNN stannin
SRSF6 serine/arginine-rich splicing factor 6
STK26 serine/threonine protein kinase 26
TGFB1 transforming growth factor, beta 1
TPM1 tropomyosin 1 (alpha)
TRIB2 tribbles pseudokinase 2