BRD-A17016119_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A17016119_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA2 carbonic anhydrase II
CPB1 carboxypeptidase B1 (tissue)
CX3CR1 chemokine (C-X3-C motif) receptor 1
EXT1 exostosin glycosyltransferase 1
FAM69A family with sequence similarity 69, member A
HOXD1 homeobox D1
PVRL3 poliovirus receptor-related 3
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
SNX7 sorting nexin 7
SST somatostatin
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
CNPY3 canopy FGF signaling regulator 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
ENO2 enolase 2 (gamma, neuronal)
ESR1 estrogen receptor 1
GADD45B growth arrest and DNA-damage-inducible, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
KYNU kynureninase
MT1X metallothionein 1X
NR2F2 nuclear receptor subfamily 2, group F, member 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SELL selectin L
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TFF1 trefoil factor 1
TSC22D1 TSC22 domain family, member 1
TSPAN13 tetraspanin 13