BRD-A16998493_etodolac_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-A16998493_etodolac_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ANKRD10 ankyrin repeat domain 10
ARHGAP29 Rho GTPase activating protein 29
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CD200 CD200 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD9 CD9 molecule
CPB1 carboxypeptidase B1 (tissue)
CRISP3 cysteine-rich secretory protein 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCLK1 doublecortin-like kinase 1
DEPTOR DEP domain containing MTOR-interacting protein
DMXL2 Dmx-like 2
DUSP10 dual specificity phosphatase 10
DYNLT3 dynein, light chain, Tctex-type 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
LAMP2 lysosomal-associated membrane protein 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOC100505650 uncharacterized LOC100505650
LY96 lymphocyte antigen 96
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MSLN mesothelin
MTSS1 metastasis suppressor 1
MUC16 mucin 16, cell surface associated
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NRIP1 nuclear receptor interacting protein 1
PDE10A phosphodiesterase 10A
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAP2C RAP2C, member of RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNF6 ring finger protein (C3H2C3 type) 6
S100A8 S100 calcium binding protein A8
SERINC5 serine incorporator 5
SGK1 serum/glucocorticoid regulated kinase 1
SLC38A6 solute carrier family 38, member 6
SLPI secretory leukocyte peptidase inhibitor
SMC1A structural maintenance of chromosomes 1A
SNAP23 synaptosomal-associated protein, 23kDa
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPTSSA serine palmitoyltransferase, small subunit A
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STS steroid sulfatase (microsomal), isozyme S
TFPI2 tissue factor pathway inhibitor 2
TMEM30B transmembrane protein 30B
TPD52L1 tumor protein D52-like 1
TSC22D1 TSC22 domain family, member 1
TSPAN12 tetraspanin 12
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
AK4 adenylate kinase 4
B3GNT1
CD99 CD99 molecule
COL1A1 collagen, type I, alpha 1
CTSG cathepsin G
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERP29 endoplasmic reticulum protein 29
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASN fatty acid synthase
FLNA filamin A, alpha
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KDM5D lysine (K)-specific demethylase 5D
LTBP3 latent transforming growth factor beta binding protein 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NREP neuronal regeneration related protein
PEBP1 phosphatidylethanolamine binding protein 1
PLK1 polo-like kinase 1
PNMA1 paraneoplastic Ma antigen 1
PPIF peptidylprolyl isomerase F
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS21 ribosomal protein S21
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SET SET nuclear proto-oncogene
SFN stratifin
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPINK1 serine peptidase inhibitor, Kazal type 1
TP53 tumor protein p53
UBE2S ubiquitin-conjugating enzyme E2S
UGDH UDP-glucose 6-dehydrogenase
VCAN versican
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1