BRD-A16998493_etodolac_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A16998493_etodolac_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM1 absent in melanoma 1
ARHGAP29 Rho GTPase activating protein 29
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BLNK B-cell linker
CA2 carbonic anhydrase II
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CPB1 carboxypeptidase B1 (tissue)
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
DENND1B DENN/MADD domain containing 1B
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DOCK4 dedicator of cytokinesis 4
EXT1 exostosin glycosyltransferase 1
FKBP4 FK506 binding protein 4, 59kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HSPA4 heat shock 70kDa protein 4
IPO13 importin 13
LMO3 LIM domain only 3 (rhombotin-like 2)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1A1 mannosidase, alpha, class 1A, member 1
MPZL2 myelin protein zero-like 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NELL2 NEL-like 2 (chicken)
OSBPL10 oxysterol binding protein-like 10
PEG10 paternally expressed 10
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMM2 phosphomannomutase 2
PON3 paraoxonase 3
POU2AF1 POU class 2 associating factor 1
PTK2 protein tyrosine kinase 2
PTPRK protein tyrosine phosphatase, receptor type, K
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFTN1 raftlin, lipid raft linker 1
SDC1 syndecan 1
SHB Src homology 2 domain containing adaptor protein B
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CALM1 calmodulin 1 (phosphorylase kinase, delta)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
FOLR1 folate receptor 1 (adult)
GPM6B glycoprotein M6B
GSTA4 glutathione S-transferase alpha 4
GSTM3 glutathione S-transferase mu 3 (brain)
HK1 hexokinase 1
HN1 hematological and neurological expressed 1
IL6ST interleukin 6 signal transducer
MGP matrix Gla protein
PENK proenkephalin
PLP1 proteolipid protein 1
PLTP phospholipid transfer protein
PTGES prostaglandin E synthase
RCN3 reticulocalbin 3, EF-hand calcium binding domain
S100A11 S100 calcium binding protein A11
S100B S100 calcium binding protein B
SMAD2 SMAD family member 2