BRD-A16998493_etodolac_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A16998493_etodolac_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
AUTS2 autism susceptibility candidate 2
BTG2 BTG family, member 2
C5AR1 complement component 5a receptor 1
CA2 carbonic anhydrase II
CFD complement factor D (adipsin)
COL4A5 collagen, type IV, alpha 5
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
ESRP1 epithelial splicing regulatory protein 1
FAM198B family with sequence similarity 198, member B
FRY furry homolog (Drosophila)
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGN4 high mobility group nucleosomal binding domain 4
HOXB6 homeobox B6
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT18 keratin 18, type I
MAOA monoamine oxidase A
MPZL2 myelin protein zero-like 2
NUAK1 NUAK family, SNF1-like kinase, 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PON3 paraoxonase 3
RAD21 RAD21 homolog (S. pombe)
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
SCGB2A1 secretoglobin, family 2A, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STS steroid sulfatase (microsomal), isozyme S
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EBP emopamil binding protein (sterol isomerase)
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FSTL1 follistatin-like 1
HN1 hematological and neurological expressed 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
KRT10 keratin 10, type I
MIA melanoma inhibitory activity
NOLC1 nucleolar and coiled-body phosphoprotein 1
PGAM1 phosphoglycerate mutase 1 (brain)
PMEPA1 prostate transmembrane protein, androgen induced 1
PRSS3 protease, serine, 3
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTX3 pentraxin 3, long
QDPR quinoid dihydropteridine reductase
RBM34 RNA binding motif protein 34
RBMS1 RNA binding motif, single stranded interacting protein 1
RCAN1 regulator of calcineurin 1
RET ret proto-oncogene
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
RPS26 ribosomal protein S26
S100A2 S100 calcium binding protein A2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLIRP SRA stem-loop interacting RNA binding protein
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TECR trans-2,3-enoyl-CoA reductase
TFF3 trefoil factor 3 (intestinal)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSPAN3 tetraspanin 3
TUBB2B tubulin, beta 2B class IIb
ZCCHC24 zinc finger, CCHC domain containing 24