BRD-A16820783_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A16820783_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CALD1 caldesmon 1
CBR3 carbonyl reductase 3
CCNA2 cyclin A2
CCNB2 cyclin B2
CCNF cyclin F
CD36 CD36 molecule (thrombospondin receptor)
CD93 CD93 molecule
CDC25B cell division cycle 25B
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDK14 cyclin-dependent kinase 14
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CEP55 centrosomal protein 55kDa
CXADR coxsackie virus and adenovirus receptor
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
GTSE1 G-2 and S-phase expressed 1
HEBP1 heme binding protein 1
HIST1H2BG histone cluster 1, H2bg
HJURP Holliday junction recognition protein
HMMR hyaluronan-mediated motility receptor (RHAMM)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JUN jun proto-oncogene
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
MACF1 microtubule-actin crosslinking factor 1
MKI67 marker of proliferation Ki-67
NDC80 NDC80 kinetochore complex component
NEK2 NIMA-related kinase 2
NES nestin
PLK1 polo-like kinase 1
PRC1 protein regulator of cytokinesis 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SPAG5 sperm associated antigen 5
TACSTD2 tumor-associated calcium signal transducer 2
TMSB15A thymosin beta 15a
TPX2 TPX2, microtubule-associated
TTK TTK protein kinase

decreased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BLNK B-cell linker
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
GCLC glutamate-cysteine ligase, catalytic subunit
IL13RA2 interleukin 13 receptor, alpha 2
KRT19 keratin 19, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MDK midkine (neurite growth-promoting factor 2)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MET MET proto-oncogene, receptor tyrosine kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
SPATA20 spermatogenesis associated 20
TF transferrin
TMEM176B transmembrane protein 176B
TNS1 tensin 1
TPD52 tumor protein D52
TSPAN8 tetraspanin 8
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNG uracil-DNA glycosylase