BRD-A16820783_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A16820783_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AREG amphiregulin
C5AR1 complement component 5a receptor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CPB1 carboxypeptidase B1 (tissue)
CSNK1E casein kinase 1, epsilon
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DLC1 DLC1 Rho GTPase activating protein
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
GAL galanin/GMAP prepropeptide
JMJD6 jumonji domain containing 6
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LIMS1 LIM and senescent cell antigen-like domains 1
MFAP5 microfibrillar associated protein 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NNMT nicotinamide N-methyltransferase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PODXL podocalyxin-like
RGS1 regulator of G-protein signaling 1
RHOB ras homolog family member B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEC61B Sec61 beta subunit
SEPT6 septin 6
SERINC5 serine incorporator 5
SIK1 salt-inducible kinase 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TIMP3 TIMP metallopeptidase inhibitor 3
TPM4 tropomyosin 4
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BANF1 barrier to autointegration factor 1
CDK1 cyclin-dependent kinase 1
CLU clusterin
ETV1 ets variant 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GNPDA1 glucosamine-6-phosphate deaminase 1
GSTM3 glutathione S-transferase mu 3 (brain)
HMGA2 high mobility group AT-hook 2
HOXA10 homeobox A10
LIPA lipase A, lysosomal acid, cholesterol esterase
MBP myelin basic protein
MCM2 minichromosome maintenance complex component 2
MDK midkine (neurite growth-promoting factor 2)
NQO1 NAD(P)H dehydrogenase, quinone 1
NREP neuronal regeneration related protein
PCNA proliferating cell nuclear antigen
PRNP prion protein
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
ZFPM2 zinc finger protein, FOG family member 2
ZWINT ZW10 interacting kinetochore protein