BRD-A16820783_-666_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A16820783_-666_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AREG amphiregulin
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLDN3 claudin 3
CXCL2 chemokine (C-X-C motif) ligand 2
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
ITM2A integral membrane protein 2A
JAG1 jagged 1
LAMB3 laminin, beta 3
LDOC1 leucine zipper, down-regulated in cancer 1
LRP4 low density lipoprotein receptor-related protein 4
MET MET proto-oncogene, receptor tyrosine kinase
NFIB nuclear factor I/B
PCCB propionyl CoA carboxylase, beta polypeptide
PDGFA platelet-derived growth factor alpha polypeptide
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SIK1 salt-inducible kinase 1
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRGN serglycin
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CAST calpastatin
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBLN1 fibulin 1
GRB14 growth factor receptor-bound protein 14
HOXA5 homeobox A5
HOXB2 homeobox B2
HSPA2 heat shock 70kDa protein 2
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT23 keratin 23, type I
MTSS1 metastasis suppressor 1
NUSAP1 nucleolar and spindle associated protein 1
PBX3 pre-B-cell leukemia homeobox 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TGM2 transglutaminase 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TUBB6 tubulin, beta 6 class V