BRD-A16820783_-666_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

93 genes differentially expressed following the BRD-A16820783_-666_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN4 actinin, alpha 4
ADGRG1 adhesion G protein-coupled receptor G1
ALCAM activated leukocyte cell adhesion molecule
ANPEP alanyl (membrane) aminopeptidase
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOD apolipoprotein D
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAPN1 calpain 1, (mu/I) large subunit
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CD47 CD47 molecule
CFH complement factor H
CFLAR CASP8 and FADD-like apoptosis regulator
CTBP2 C-terminal binding protein 2
CTSW cathepsin W
DCLK1 doublecortin-like kinase 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EFHD1 EF-hand domain family, member D1
FABP7 fatty acid binding protein 7, brain
FNDC3B fibronectin type III domain containing 3B
FZD7 frizzled class receptor 7
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLIPR1 GLI pathogenesis-related 1
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GRB10 growth factor receptor-bound protein 10
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGSF3 immunoglobulin superfamily, member 3
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
KRT7 keratin 7, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MAP1B microtubule-associated protein 1B
MBNL1 muscleblind-like splicing regulator 1
MGLL monoglyceride lipase
MRPS2 mitochondrial ribosomal protein S2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NFIB nuclear factor I/B
PDZK1IP1 PDZK1 interacting protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G16 phospholipase A2, group XVI
PLAGL1 pleiomorphic adenoma gene-like 1
PLAU plasminogen activator, urokinase
PNMA2 paraneoplastic Ma antigen 2
PRSS3 protease, serine, 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYGB phosphorylase, glycogen; brain
RCAN1 regulator of calcineurin 1
SCGB2A2 secretoglobin, family 2A, member 2
SCPEP1 serine carboxypeptidase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRI sorcin
SRPX sushi-repeat containing protein, X-linked
STC1 stanniocalcin 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMP1 TIMP metallopeptidase inhibitor 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPD52 tumor protein D52
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ATF5 activating transcription factor 5
BAMBI BMP and activin membrane-bound inhibitor
C1QA complement component 1, q subcomponent, A chain
CADM1 cell adhesion molecule 1
COG7 component of oligomeric golgi complex 7
CXCL12 chemokine (C-X-C motif) ligand 12
ESR1 estrogen receptor 1
GLUL glutamate-ammonia ligase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ISOC1 isochorismatase domain containing 1
KEAP1 kelch-like ECH-associated protein 1
MEIS2 Meis homeobox 2
SFRP4 secreted frizzled-related protein 4
SIK1 salt-inducible kinase 1
TTN titin
TUBB6 tubulin, beta 6 class V
ZNF586 zinc finger protein 586