BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AMD1 adenosylmethionine decarboxylase 1
CCDC85B coiled-coil domain containing 85B
CTPS1 CTP synthase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GRWD1 glutamate-rich WD repeat containing 1
GTPBP8 GTP-binding protein 8 (putative)
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NFIB nuclear factor I/B
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PRR7 proline rich 7 (synaptic)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPATA20 spermatogenesis associated 20
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNPO1 transportin 1
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADA adenosine deaminase
ADM adrenomedullin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD86 CD86 molecule
CLU clusterin
DPYSL3 dihydropyrimidinase-like 3
DSG2 desmoglein 2
FOLR1 folate receptor 1 (adult)
HIST1H2BG histone cluster 1, H2bg
IER5 immediate early response 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL13RA1 interleukin 13 receptor, alpha 1
ITFG1 integrin alpha FG-GAP repeat containing 1
LGALS1 lectin, galactoside-binding, soluble, 1
NEK2 NIMA-related kinase 2
PLXNB2 plexin B2
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TNNT1 troponin T type 1 (skeletal, slow)
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1