BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
C3 complement component 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CSRP1 cysteine and glycine-rich protein 1
CXCL2 chemokine (C-X-C motif) ligand 2
DCLK1 doublecortin-like kinase 1
FAIM Fas apoptotic inhibitory molecule
GLRX glutaredoxin (thioltransferase)
HMOX1 heme oxygenase 1
ISOC1 isochorismatase domain containing 1
LIMCH1 LIM and calponin homology domains 1
LPL lipoprotein lipase
NFIB nuclear factor I/B
PDZD2 PDZ domain containing 2
POSTN periostin, osteoblast specific factor
PXDN peroxidasin
SFRP1 secreted frizzled-related protein 1
SOBP sine oculis binding protein homolog (Drosophila)
SOX11 SRY (sex determining region Y)-box 11

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ALCAM activated leukocyte cell adhesion molecule
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
HLA-B major histocompatibility complex, class I, B
KRAS Kirsten rat sarcoma viral oncogene homolog
PSPH phosphoserine phosphatase
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1