BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCND2 cyclin D2
CD52 CD52 molecule
CES1 carboxylesterase 1
EIF5A eukaryotic translation initiation factor 5A
EXT1 exostosin glycosyltransferase 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FILIP1L filamin A interacting protein 1-like
FXYD5 FXYD domain containing ion transport regulator 5
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNLY granulysin
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IQGAP1 IQ motif containing GTPase activating protein 1
LPAR6 lysophosphatidic acid receptor 6
MEIS2 Meis homeobox 2
MYO1F myosin IF
PBX3 pre-B-cell leukemia homeobox 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRO protein tyrosine phosphatase, receptor type, O
PYCARD PYD and CARD domain containing
S100A8 S100 calcium binding protein A8
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SHB Src homology 2 domain containing adaptor protein B
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
STK10 serine/threonine kinase 10
STON1 stonin 1
TCEAL2 transcription elongation factor A (SII)-like 2
TESK1 testis-specific kinase 1
TKTL1 transketolase-like 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
AQP3 aquaporin 3 (Gill blood group)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CKB creatine kinase, brain
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CRIP1 cysteine-rich protein 1 (intestinal)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DLC1 DLC1 Rho GTPase activating protein
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46A family with sequence similarity 46, member A
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GSN gelsolin
HMGN3 high mobility group nucleosomal binding domain 3
MALL mal, T-cell differentiation protein-like
MARCKS myristoylated alanine-rich protein kinase C substrate
MT1M metallothionein 1M
NPY neuropeptide Y
PEBP1 phosphatidylethanolamine binding protein 1
PKM pyruvate kinase, muscle
PLAT plasminogen activator, tissue
PMP22 peripheral myelin protein 22
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPATA20 spermatogenesis associated 20
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCTA T-cell leukemia translocation altered
TM4SF1 transmembrane 4 L six family member 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta