BRD-A16581344_7226698_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A16581344_7226698_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP7 A kinase (PRKA) anchor protein 7
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AQP3 aquaporin 3 (Gill blood group)
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
C6ORF48 chromosome 6 open reading frame 48
CAST calpastatin
ECI2 enoyl-CoA delta isomerase 2
GDF15 growth differentiation factor 15
GNAS GNAS complex locus
HOXC6 homeobox C6
LMNA lamin A/C
LTBP3 latent transforming growth factor beta binding protein 3
MARCKSL1 MARCKS-like 1
MDK midkine (neurite growth-promoting factor 2)
NRN1 neuritin 1
PRAME preferentially expressed antigen in melanoma
PRKCH protein kinase C, eta
QDPR quinoid dihydropteridine reductase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
TKT transketolase
TMEM47 transmembrane protein 47
YBX3 Y box binding protein 3

decreased expression

Symbol Name
AURKB aurora kinase B
CADM1 cell adhesion molecule 1
CELF2 CUGBP, Elav-like family member 2
CLEC2B C-type lectin domain family 2, member B
EIF5 eukaryotic translation initiation factor 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FRS2 fibroblast growth factor receptor substrate 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGKC immunoglobulin kappa constant
KIAA0196 KIAA0196
NOTCH1 notch 1
P3H2 prolyl 3-hydroxylase 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POSTN periostin, osteoblast specific factor
RAD51C RAD51 paralog C
RRM2 ribonucleotide reductase M2
RSU1 Ras suppressor protein 1
SULF1 sulfatase 1
TGFB3 transforming growth factor, beta 3
THBS2 thrombospondin 2