BRD-A16332958_Modafinil_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

112 genes differentially expressed following the BRD-A16332958_Modafinil_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
ARHGAP29 Rho GTPase activating protein 29
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
BGN biglycan
CALD1 caldesmon 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
CDC25B cell division cycle 25B
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
CPE carboxypeptidase E
CRP C-reactive protein, pentraxin-related
CXCL9 chemokine (C-X-C motif) ligand 9
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DEFA4 defensin, alpha 4, corticostatin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
DSP desmoplakin
EDN1 endothelin 1
EIF5A eukaryotic translation initiation factor 5A
FILIP1L filamin A interacting protein 1-like
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
HHEX hematopoietically expressed homeobox
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXD1 homeobox D1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL32 interleukin 32
LPAR6 lysophosphatidic acid receptor 6
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MXRA5 matrix-remodelling associated 5
NID1 nidogen 1
OLFM4 olfactomedin 4
ORM1 orosomucoid 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PERP PERP, TP53 apoptosis effector
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PON3 paraoxonase 3
PRUNE2 prune homolog 2 (Drosophila)
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SDC1 syndecan 1
SDC2 syndecan 2
SPON2 spondin 2, extracellular matrix protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SULF1 sulfatase 1
THBS2 thrombospondin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM176B transmembrane protein 176B
TMEM45A transmembrane protein 45A
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TUBA4A tubulin, alpha 4a

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ANXA5 annexin A5
BLVRB biliverdin reductase B
BST2 bone marrow stromal cell antigen 2
C6ORF48 chromosome 6 open reading frame 48
CDC42 cell division cycle 42
COCH cochlin
COG7 component of oligomeric golgi complex 7
CST3 cystatin C
CTSB cathepsin B
CTTN cortactin
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
GRIA2 glutamate receptor, ionotropic, AMPA 2
HEBP1 heme binding protein 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IFI44L interferon-induced protein 44-like
IRS2 insulin receptor substrate 2
KDM5D lysine (K)-specific demethylase 5D
MEIS1 Meis homeobox 1
NAV3 neuron navigator 3
NEK7 NIMA-related kinase 7
NMB neuromedin B
NME4 NME/NM23 nucleoside diphosphate kinase 4
NOTCH2NL notch 2 N-terminal like
NPC2 Niemann-Pick disease, type C2
PTER phosphotriesterase related
RBP1 retinol binding protein 1, cellular
S100A2 S100 calcium binding protein A2
SLPI secretory leukocyte peptidase inhibitor
SNX11 sorting nexin 11
TIMP4 TIMP metallopeptidase inhibitor 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM100 transmembrane protein 100
UFM1 ubiquitin-fold modifier 1
VLDLR very low density lipoprotein receptor