BRD-A15530910_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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38 genes differentially expressed following the BRD-A15530910_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ALDOC aldolase C, fructose-bisphosphate
BTG2 BTG family, member 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRABP2 cellular retinoic acid binding protein 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DUSP5 dual specificity phosphatase 5
ECM1 extracellular matrix protein 1
FABP7 fatty acid binding protein 7, brain
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FGFBP1 fibroblast growth factor binding protein 1
GLUL glutamate-ammonia ligase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IL32 interleukin 32
INSIG1 insulin induced gene 1
KLK10 kallikrein-related peptidase 10
KRT6A keratin 6A, type II
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
S100A8 S100 calcium binding protein A8
SC5D sterol-C5-desaturase
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
PLAGL1 pleiomorphic adenoma gene-like 1
TFRC transferrin receptor
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)