BRD-A15435692_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-A15435692_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
DFNA5 deafness, autosomal dominant 5
EGFR epidermal growth factor receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGLV2-23 immunoglobulin lambda variable 2-23
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT17 keratin 17, type I
MTSS1 metastasis suppressor 1
NXN nucleoredoxin
PI3 peptidase inhibitor 3, skin-derived
RAB38 RAB38, member RAS oncogene family
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSKU tsukushi, small leucine rich proteoglycan
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
CKS2 CDC28 protein kinase regulatory subunit 2
CLC Charcot-Leyden crystal galectin
CLIC4 chloride intracellular channel 4
CYBA cytochrome b-245, alpha polypeptide
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FAM120A family with sequence similarity 120A
FGF13 fibroblast growth factor 13
FOSB FBJ murine osteosarcoma viral oncogene homolog B
G0S2 G0/G1 switch 2
HOXC6 homeobox C6
ITM2A integral membrane protein 2A
LMO2 LIM domain only 2 (rhombotin-like 1)
MAP7 microtubule-associated protein 7
MSLN mesothelin
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
NNMT nicotinamide N-methyltransferase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PRKD3 protein kinase D3
QPCT glutaminyl-peptide cyclotransferase
S100P S100 calcium binding protein P
SCG3 secretogranin III
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SF1 splicing factor 1
SGK1 serum/glucocorticoid regulated kinase 1
ZBTB10 zinc finger and BTB domain containing 10