BRD-A15131297_Benazepril hydrochloride_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

90 genes differentially expressed following the BRD-A15131297_Benazepril hydrochloride_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CD86 CD86 molecule
CD9 CD9 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DEPTOR DEP domain containing MTOR-interacting protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EMX2 empty spiracles homeobox 2
ESR1 estrogen receptor 1
FST follistatin
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GJA1 gap junction protein, alpha 1, 43kDa
GREM1 gremlin 1, DAN family BMP antagonist
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
JUP junction plakoglobin
KRT14 keratin 14, type I
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEA15 phosphoprotein enriched in astrocytes 15
QPCT glutaminyl-peptide cyclotransferase
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SMC1A structural maintenance of chromosomes 1A
SOSTDC1 sclerostin domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
VCAN versican
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ADGRA3 adhesion G protein-coupled receptor A3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ANXA3 annexin A3
ARFIP2 ADP-ribosylation factor interacting protein 2
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BAD BCL2-associated agonist of cell death
BST2 bone marrow stromal cell antigen 2
CDK6 cyclin-dependent kinase 6
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSK c-src tyrosine kinase
CTSC cathepsin C
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FOLR1 folate receptor 1 (adult)
HSPA4L heat shock 70kDa protein 4-like
KDM5D lysine (K)-specific demethylase 5D
LPIN2 lipin 2
MCOLN1 mucolipin 1
MLEC malectin
MT1E metallothionein 1E
MTA1 metastasis associated 1
PLAC8 placenta-specific 8
RNASET2 ribonuclease T2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEPP1 selenoprotein P, plasma, 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SORD sorbitol dehydrogenase
SPTBN1 spectrin, beta, non-erythrocytic 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TSPAN8 tetraspanin 8
YME1L1 YME1-like 1 ATPase