BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CREB3L2 cAMP responsive element binding protein 3-like 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GRB10 growth factor receptor-bound protein 10
IDS iduronate 2-sulfatase
IGL immunoglobulin lambda locus
ISG20 interferon stimulated exonuclease gene 20kDa
KCNK1 potassium channel, two pore domain subfamily K, member 1
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MIR22HG MIR22 host gene
MSLN mesothelin
MYO6 myosin VI
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC4 syndecan 4
SOX4 SRY (sex determining region Y)-box 4
SQSTM1 sequestosome 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2

decreased expression

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
CDC7 cell division cycle 7
DACH1 dachshund family transcription factor 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MSMO1 methylsterol monooxygenase 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
S100A8 S100 calcium binding protein A8
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
UNG uracil-DNA glycosylase
ZNF652 zinc finger protein 652