BRD-A15010982_10006350_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-A15010982_10006350_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADM adrenomedullin
APOD apolipoprotein D
ASPN asporin
CD36 CD36 molecule (thrombospondin receptor)
CD59 CD59 molecule, complement regulatory protein
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CTSK cathepsin K
CXCL14 chemokine (C-X-C motif) ligand 14
ECM1 extracellular matrix protein 1
EMP1 epithelial membrane protein 1
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FDFT1 farnesyl-diphosphate farnesyltransferase 1
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
JCHAIN joining chain of multimeric IgA and IgM
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
QPCT glutaminyl-peptide cyclotransferase
RGS5 regulator of G-protein signaling 5
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERINC5 serine incorporator 5
SFRP4 secreted frizzled-related protein 4
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
H2AFZ H2A histone family, member Z
HMGB2 high mobility group box 2
HSPA8 heat shock 70kDa protein 8
KRT7 keratin 7, type II
MET MET proto-oncogene, receptor tyrosine kinase
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLK2 polo-like kinase 2
TES testin LIM domain protein
TYMS thymidylate synthetase