BRD-A14985772_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-A14985772_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM1 absent in melanoma 1
ASS1 argininosuccinate synthase 1
C1S complement component 1, s subcomponent
CBR1 carbonyl reductase 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCND2 cyclin D2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC11A C-type lectin domain family 11, member A
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CTSB cathepsin B
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F13A1 coagulation factor XIII, A1 polypeptide
FAM129A family with sequence similarity 129, member A
FAM169A family with sequence similarity 169, member A
FOLR1 folate receptor 1 (adult)
GLUL glutamate-ammonia ligase
GREB1 growth regulation by estrogen in breast cancer 1
HLF hepatic leukemia factor
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
KDM5D lysine (K)-specific demethylase 5D
KIF1A kinesin family member 1A
KRT14 keratin 14, type I
KRT23 keratin 23, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LINC00341 long intergenic non-protein coding RNA 341
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MKNK2 MAP kinase interacting serine/threonine kinase 2
MT1E metallothionein 1E
MXRA7 matrix-remodelling associated 7
NSG1 neuron specific gene family member 1
PLSCR3 phospholipid scramblase 3
RBP1 retinol binding protein 1, cellular
REEP5 receptor accessory protein 5
RORA RAR-related orphan receptor A
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRT3 sirtuin 3
SYT1 synaptotagmin I
TSC22D3 TSC22 domain family, member 3
VAMP5 vesicle-associated membrane protein 5
VSNL1 visinin-like 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM28 ADAM metallopeptidase domain 28
BNC2 basonuclin 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FBXL12 F-box and leucine-rich repeat protein 12
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
GATA6 GATA binding protein 6
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JCHAIN joining chain of multimeric IgA and IgM
LAMA4 laminin, alpha 4
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA3 melanoma antigen family A3
MAP7 microtubule-associated protein 7
MCTP1 multiple C2 domains, transmembrane 1
PBX3 pre-B-cell leukemia homeobox 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
RGS5 regulator of G-protein signaling 5
RPS5 ribosomal protein S5
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMAD3 SMAD family member 3
SOCS2 suppressor of cytokine signaling 2
SRGN serglycin
TLR4 toll-like receptor 4
TNPO1 transportin 1
TOB1 transducer of ERBB2, 1
TUSC3 tumor suppressor candidate 3
VNN1 vanin 1
VWF von Willebrand factor
ZEB1 zinc finger E-box binding homeobox 1
ZNF652 zinc finger protein 652