BRD-A14966924_ALAPROCLATE_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

127 genes differentially expressed following the BRD-A14966924_ALAPROCLATE_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDOB aldolase B, fructose-bisphosphate
AQP3 aquaporin 3 (Gill blood group)
ASPN asporin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CALML3 calmodulin-like 3
CD52 CD52 molecule
CD9 CD9 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHGB chromogranin B
CLDN8 claudin 8
COL3A1 collagen, type III, alpha 1
CTNND1 catenin (cadherin-associated protein), delta 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DENND1B DENN/MADD domain containing 1B
EPCAM epithelial cell adhesion molecule
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP1 fatty acid binding protein 1, liver
FAM198B family with sequence similarity 198, member B
FBP1 fructose-1,6-bisphosphatase 1
FBXL12 F-box and leucine-rich repeat protein 12
FCGBP Fc fragment of IgG binding protein
FDX1 ferredoxin 1
FGFR2 fibroblast growth factor receptor 2
FKBP5 FK506 binding protein 5
FXYD6 FXYD domain containing ion transport regulator 6
FZD5 frizzled class receptor 5
GNAS GNAS complex locus
GREM1 gremlin 1, DAN family BMP antagonist
HIST2H2BE histone cluster 2, H2be
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IVNS1ABP influenza virus NS1A binding protein
LRRN3 leucine rich repeat neuronal 3
LUM lumican
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MREG melanoregulin
MSMB microseminoprotein, beta-
MT1G metallothionein 1G
MTSS1 metastasis suppressor 1
MYO1B myosin IB
NEBL nebulette
NVL nuclear VCP-like
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PEG3 paternally expressed 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCL1 phospholipase C-like 1
POSTN periostin, osteoblast specific factor
PRR15L proline rich 15-like
RAI14 retinoic acid induced 14
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A14 S100 calcium binding protein A14
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SQRDL sulfide quinone reductase-like (yeast)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TBX2 T-box 2
TBXA2R thromboxane A2 receptor
TCF21 transcription factor 21
TCTA T-cell leukemia translocation altered
THBS1 thrombospondin 1
TMC5 transmembrane channel-like 5
TMEM176B transmembrane protein 176B
TMEM30B transmembrane protein 30B
VEGFA vascular endothelial growth factor A
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AXL AXL receptor tyrosine kinase
BMI1 BMI1 proto-oncogene, polycomb ring finger
CADM1 cell adhesion molecule 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CST3 cystatin C
CXCL5 chemokine (C-X-C motif) ligand 5
CYBA cytochrome b-245, alpha polypeptide
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
FXYD5 FXYD domain containing ion transport regulator 5
GAS1 growth arrest-specific 1
GPATCH8 G patch domain containing 8
GPX3 glutathione peroxidase 3
HMGN3 high mobility group nucleosomal binding domain 3
HOXC6 homeobox C6
ITM2A integral membrane protein 2A
MYO6 myosin VI
NNMT nicotinamide N-methyltransferase
NRN1 neuritin 1
NTS neurotensin
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDGFA platelet-derived growth factor alpha polypeptide
PFN2 profilin 2
PLA2G16 phospholipase A2, group XVI
PLS3 plastin 3
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PRDX2 peroxiredoxin 2
PRSS2 protease, serine, 2 (trypsin 2)
SELL selectin L
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
TFF1 trefoil factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIAM1 T-cell lymphoma invasion and metastasis 1
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB18 zinc finger and BTB domain containing 18