BRD-A14798026_-666_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-A14798026_-666_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX2 armadillo repeat containing, X-linked 2
BTG2 BTG family, member 2
CCND2 cyclin D2
CPOX coproporphyrinogen oxidase
DLX2 distal-less homeobox 2
DUSP2 dual specificity phosphatase 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
HMGB2 high mobility group box 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
MDFIC MyoD family inhibitor domain containing
MFSD10 major facilitator superfamily domain containing 10
MYB v-myb avian myeloblastosis viral oncogene homolog
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAT ornithine aminotransferase
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
SERINC5 serine incorporator 5
SFRP4 secreted frizzled-related protein 4
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SOCS2 suppressor of cytokine signaling 2
SST somatostatin
SYNJ2 synaptojanin 2
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
UBE2J1 ubiquitin-conjugating enzyme E2, J1

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSL1 acyl-CoA synthetase long-chain family member 1
AGTR1 angiotensin II receptor, type 1
AHNAK2 AHNAK nucleoprotein 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AOX1 aldehyde oxidase 1
APOC1 apolipoprotein C-I
BEX1 brain expressed, X-linked 1
CD59 CD59 molecule, complement regulatory protein
CFI complement factor I
CLTA clathrin, light chain A
COA3 cytochrome c oxidase assembly factor 3
CSTA cystatin A (stefin A)
CTSC cathepsin C
CTSH cathepsin H
CYB5A cytochrome b5 type A (microsomal)
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP1 dual specificity phosphatase 1
DUSP3 dual specificity phosphatase 3
FADS1 fatty acid desaturase 1
FLRT3 fibronectin leucine rich transmembrane protein 3
GPX4 glutathione peroxidase 4
HOXA5 homeobox A5
HSPB1 heat shock 27kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KRT14 keratin 14, type I
MAP1B microtubule-associated protein 1B
MRPS16 mitochondrial ribosomal protein S16
MYO1B myosin IB
NFIB nuclear factor I/B
NRIP1 nuclear receptor interacting protein 1
NT5DC2 5'-nucleotidase domain containing 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PGM1 phosphoglucomutase 1
PI3 peptidase inhibitor 3, skin-derived
RAB13 RAB13, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLPI secretory leukocyte peptidase inhibitor
SYNE2 spectrin repeat containing, nuclear envelope 2
TAGLN2 transgelin 2
TSPAN4 tetraspanin 4
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
VAT1 vesicle amine transport 1
VCAN versican
VKORC1 vitamin K epoxide reductase complex, subunit 1